Winter School 2014
Program of the 2014 IRTG Winter School
4th Winter School of the Collaborative Research Centre TRR81
“Chromatin Changes in Differentiation and Malignancies” Marburg-Giessen-Bad Nauheim-Rotterdam
at the Kleinwalsertal, February 16 – February 21, 2014
Sunday 16.2.2014
20:15 Ski Rental
Monday 17.2.2014
MORNING SESSION
09:00-11:30
Chair: Ruben Boers and Angelina Georgieva
Welcome at the seminar room
- Karim Bouazoune (PI Brehm M) Chromatin remodeling by the CHD7 protein is impaired by mutations that cause human developmental disorders
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Ina Theofel (PI Rathke M) tBRD-1 interacts with two new members of the BET family and is required for gene activation in male germ cells
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Dino Giaimo (PI Borggrefe GI) The core RBP-J repressor complex containing MLL/KMT2D facilitates Notch transcriptional responses
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Marti Quevedo (PI Poot R) Mediator and Super-Enhancers in Neural Stem Cells
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Angelina Georgieva (PI Braun/Zhou BN) Sirt6 mediated H3K9 and H3K56 deacetylation, skeletal muscle stem cell homeostasis and muscle fiber specification
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Martin Schneider (PI Dammann GI) Impact of CCCTC-binding factor (CTCF) on epigenetic regulation of tumor suppressor genes
12:00-17:00 Open Discussions
17:30-18:15 Dinner
EVENING SESSION
18:30-21:30
Chair: Rainer Renkawitz and Sjaak Philipsen
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Uta Bauer (M) Summary of projects A02 Braun/Zhou, A03 Bauer, A04 Philipsen/Van Dijk,
A10 Stiewe -
Alexander Brehm (M) Summary of projects A06 Suske, A01 Brehm, A09 Poot, A07 Schmitz,
B02 Kracht -
Tilman Borggrefe (GI) Notch signaling controlled by chromatin modifiers
-
Danny Huylebroeck (R) Cooperation of Smad proteins with the Smad-interacting transcription factor Sip1/Zeb2 in their chromatin-binding landscape
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Joost Gribnau (R) Summary of projects B04 Galjart, B05 Wendt, B06 Dammann, B07 Dobreva, B10 Gribnau
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Jaqueline Mermoud (M) Chromatin regulation in the mammalian nucleus mediated by ATP-dependent chromatin remodeling complexes
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Willy Baarends (R) Summary of projects B11 Houtsmuller, B01 Grosveld, B09 Baarends
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Christina Rathke (M) Chromatin dynamics in Drosophila spermatids
Tuesday 18.2.2014
08:00-09:00 Breakfast
MORNING SESSION
09:00-11:30
Chair: Marti Quevedo and Adriana Jimenez
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Sara Völkel (PI Suske M) Differential recruitment of Sp transcription factors to chromatin
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Ruben Boers (PI Gribnau R) Xist, Xcised, Replaced; Unravelling the function of Lnc-RNA’s
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Lisa-Marie Dieterle (PI Schmitz GI) Homeodomain-interacting protein kinase 2:
mechanisms of chromatin recruitment -
Silvia Hernandez (PI Galjart R) Reconsitution of wild type and mutant GFP-CTCF expression in embryonic stem cells lacking endogenous CTCF
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Marie-Christin Lamkowsky (PI Stiewe M) Mechanisms of gene regulation by the p53 family inhibitor ΔNp73
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Silvia Hoeboer (PI Philipsen R) Reactivation of fetal hemoglobin expression: functional analysis of candidate modifiers in vivo
12:00-17:00 Open Discussions
17:30-18:15 Dinner
EVENING SESSION
18:30-21:30
Chair: Silvia Hernandez and René Reiner Nötzold
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Sarah Meneceur (PI Dobreva BN) The role of Rnf20 in heart development
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Maarten Paul (PI Houtsmuller R) Studying DSB Repair Foci by Super Resolution Microscopy
- Kerstin Wendt (PI Wendt R) Cohesin in chromatin organization and disease
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Mike Broeders (PI Philipsen R) CRISPR/Cas9-mediated genome engineering: application
to globin gene regulation -
Tim Hundertmark (PI Rathke M) Post-meiotic chromatin changes in male germ cells of Drosophila
PI meeting in the seminar room
Wednesday 19.2.2014
Morning SESSION
9:00-11:30
Chair: Maarten Paul and Marie-Christin Lamkowsky
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Maaike Moen (PI Poot R) Transcription factor networks in neural stem cells
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Zeynep Eren (PI Renate Renkawitz-Pohl M) Protamine like 1, a newly identified chromatin component in Drosophila melanogaster seems essential for male fertility
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Andrea Enguita Marruedo (PI Baarends R) Role of the E2 ubiquitin-conjugating enzyme
HR6B during meiotic recombination and postmeiotic chromatin remodeling -
Adriana Jiménez Carrerra (PI Dammann GI) The Function of the Hippo Pathway in Gene Regulation
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Sophie Ottema (PI Galjart R) The role of CLASP2 in neurite outgrowth
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Bastian Stielow (PI Suske M) SUMOylation of the polycomb protein L3MBTL2 facilitates repression of its target genes
12:00-17:00 Open Discussions
17:30-18:15 Dinner
EVENING SESSION
18:30-21:30
Chair: Hegias Mira and Lisa-Marie Dieterle
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Niklas Wollenhaupt (PI Mermoud M) Chromatin remodeling complex SMARCAD1 in stem cells
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Kristina Kovac (PI Brehm M) Effects of cancer-relevant mutations of the chromatin remodeler CHD4 on enzymatic and biological activities
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Johan Brandsma (PI Poot R) Transcription factor action in determining cell identity
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René Reiner Nötzold (PI Bauer M) Genome-wide mapping of PRMT6 binding sites via ChIP seq
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Stefanie Riedl (PI Bauer M) Functional analysis of the histone arginine methyltransferase PRMT6
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Oriana Genolet (PI Dobreva BN) Chromatin dynamics in cell-fate decisions of Isl1+ cardiovascular progenitors
Thursday 20.2.2014
08:00-09:00 Breakfast
MORNING SESSION
09:00-11:30
Chair: Maaike Moen and Bastian Stielow
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Markus Seibert (PI Schmitz GI) Identification and characterization of new histone phosphorylation sites
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Azi Amirnasr (PI Gribnau R) Autosomal spreading of Xist revisited
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Qi Hui (PI Braun/Zhou BN) Deciphering the role of Suv4-20h1 in heart development and congenital heart diseases
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Hegias Mira Bontenbal (PI Gribnau R) Mechanisms of mammalian X chromosome inactivation
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Anna Ernst (PI Brehm M) Role of the ATP-dependent chromatin remodeler dMi-2 in the regulation of ecdysone-dependent genes
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Sjaak Philipsen Closing remarks
12:00-16:00 Open Discussions
16:00-17:30 Workshops on Perspectives
17:30-18:30 Dinner
19:00-20:00 Torch-light procession
20:00-late Farewell party
Friday 21.2.2014
Download the program in PDF format here!