Inhaltspezifische Aktionen

Publikationen J. Roth

Prof. Dr. J. Roth

Stand: 25.11.2022

 

    1. Roth J, Cleffmann G (1986).
      Pattern of DNA increase in macronuclear anlagen of Tetrahymena.
      Journal of Cell Science 83: 155-164.
    2. Roth J, Zeisberger E, Schwandt HJ (1987).
      Changes in peripheral metabolism of catecholamines in guinea-pig during thermal adaptation.
      Journal of Thermal Biology 12: 39-44.
    3. Roth J, Zeisberger E, Schwandt HJ (1988).
      Influence of increased catecholamine levels in blood plasma during cold-adaptation and intramuscular infusion on thresholds of thermoregulatory reactions in guinea-pigs.
      Journal of Comparative Physiology B 157: 855-863.
    4. Zeisberger E, Roth J, Simon E (1988).
      Changes in water balance and in release of arginine vasopressin during thermal adaptation in guinea-pigs.
      Pflügers Archiv European Journal of Physiology 412: 285-291.
    5. Cooper KE, Blähser S, Malkinson TJ, Merker G, Roth J, Zeisberger E (1988).
      Changes in body temperature and vasopressin content of brain neurons, in pregnant and non-pregnant guinea pigs, during fevers produced by Poly I: Poly C.
      Pflügers Archiv- European Journal of Physiology 412: 292-296.
    6. Zeisberger E, Roth J (1988).
      Role of catecholamines in thermoregulation of cold-adapted and newborn guinea pigs.
      In: Künzel W, Jensen A (editors), The endocrine control of the fetus, physiological and pathophysiological aspects.
      Springer Verlag, Berlin, Heidelberg, pp 288-299.
    7. Merker G, Roth J, Zeisberger E (1989).
      Thermoadaptive influence on reactivity pattern of vasopressinergic neurons in the guinea pig.
      Cellular and Molecular Life Sciences (formerly: Experientia) 45: 722-726.
    8. Zeisberger E, Roth J (1989).
      Changes in peripheral and central release of hormones during thermal adaptation in the guinea pig.
      In: Malan A, Canguilhem B (editors), Living in the cold II.
      John Libbey Eurotext Ltd, London, Paris, pp 435-444.
    9. Roth J, Merker G, Nürnberger F, Pauly B, Zeisberger E (1990).
      Changes in physiological and neuroendocrine properties during thermal adaptation of golden hamsters (Mesocricetus auratus).
      Journal of Comparative Physiology B 160: 153-159.
    10. Unger M, Merker G, Roth J, Zeisberger E (1991).
      Influence of noradrenergic input into the hypothalamic paraventricular nucleus on fever in the guinea-pig.
      Pflügers Archiv European Journal of Physiology 419: 394-400.
    11. Roth J, Zeisberger E (1992).
      Evidence for antipyretic vasopressinergic pathways and their modulation by noradrenergic afferents.
      Physiological Research 41: 49-55.
    12. Roth J, Conn C, Kluger MJ, Zeisberger E (1992).
      Release of interleukin-6 and tumor necrosis factor during l lipopolysaccharide induced fever in guinea pigs.
      In: Lomax P, Sch&oum;nbaum E (editors), Thermoregulation: The pathophysiological basis of clinical disorders.
      Karger, Basel, pp 28-32.
    13. Roth J, Schulze K, Simon E, Zeisberger E (1992).
      Alteration of endotoxin fever and release of arginine vasopressin by dehydration in the guinea pig.
      Neuroendocrinology 56: 680-686.
    14. Klir JJ, Roth J, Szelenyi Z, McClellan JL, Kluger MJ (1993).
      Role of hypothalamic interleukin-6 and tumor necrosis factor in LPS-fever in rat.
      American Journal of Physiology 265: R512-R517.
    15. Roth J, Conn CA, Kluger MJ, Zeisberger E (1993).
      Kinetics of systemic and intrahypothalamic IL-6 and tumor necrosis factor during endotoxin fever in the guinea pig.
      American Journal of Physiology 265: R653-R658.
    16. Zeisberger E, Roth J (1993).
      Neurobiological concepts of fever generation and suppression.
      Neuropsychobiology 28: 106-109.
    17. Zeisberger E, Roth J, Kluger MJ (1994).
      Interactions between the immune system and the hypothalamic neuroendocrine system during fever and endogenous antipyresis.
      In: Pleschka K, Gerstberger R (editors), Integrative and cellular aspects of autonomic functions: temperature and osmoregulation.
      John Libbey Eurotext Ltd., London, Paris, pp 181-190.
    18. Roth J, Bock M, McClellan JL, Kluger MJ, Zeisberger E (1994).
      Fever induction by a cytokine network in guinea pigs: the roles of tumor necrosis factor and interleukin-6.
      In: Milton AS (editor), Temperature Regulation: Recent Physiological and Pharmacological Advances.
      Birkhäuser, Basel, pp 11-16.
    19. Zeisberger E, Cooper KE, Kluger MJ, McClellan JL, Roth J (1994).
      Cytokines in endotoxin tolerance.
      In: Milton AS (editor), Temperature Regulation: Recent Physiological and Pharmacological Advances.
      Birkhäuser, Basel, pp 17-22.
    20. Bock M, Roth J, Kluger MJ, Zeisberger E (1994).
      Antipyresis caused by stimulation of vasopressinergic neurons and by intraseptal or systemic infusions of γ-MSH.
      American Journal of Physiology 266: R614-R621.
    21. Roth J, McClellan JL, Kluger MJ, Zeisberger E (1994).
      Attenuation of fever and systemic release of cytokines after repeated injections of bacterial lipopolysaccharide in guinea pigs.
      Journal of Physiology (London) 477.1: 177-185.
    22. Roth J, McClellan JL, Kluger MJ, Zeisberger E (1994).
      Changes in body temperature and circulating levels of interleukin-6 after intra-arterial injections or infusions of tumor necrosis factor α.
      Cellular and Molecular Life Sciences (formerly: Experientia) 50: 815-820.
    23. Jansky L, Vybiral S, Pospisilova D, Roth J, Dornand J, Zeisberger E, Kaminkova J (1994).
      Cytokine levels during the early phase of the endotoxin fever.
      In: Zeisberger E, Schönbaum E, Lomax P (editors), Thermal Balance in Health and Disease - Advances in Pharmacological Sciences.
      Birkhäuser, Basel, pp 359-362.
    24. Zeisberger E, Roth J (1994).
      Effects of immobilization on febrile, neuroendocrine and immunological responses in guinea pigs.
      In: Zeisberger E, Schönbaum E, Lomax P (editors), Thermal Balance in Health and Disease - Advances in Pharmacological Sciences.
      Birkhäuser, Basel, pp 403-408.
    25. Bock M, Roth J, Zeisberger E (1994).
      Contribution of the hypothalamic supraoptic nucleus (SON) to endogenous antipyresis in guinea pigs.
      In: Zeisberger E, Schönbaum E, Lomax P (editors), Thermal Balance in Health and Disease - Advances in Pharmacological Sciences.
      Birkhäuser, Basel, pp 421-426.
    26. Roth J, Zeisberger E (1995).
      Endotoxin tolerance alters the thermal response of guinea pigs to systemic infusions of tumor necrosis factor α.
      American Journal of Physiology 268: R514-R519.
    27. Jansky L, Vybiral S, Pospisilowa D, Roth J, Dornand J, Zeisberger E, Kaminkowa J (1995).
      Production of systemic and hypothalamic cytokines during the early phase of the endotoxin fever.
      Neuroendocrinology 62: 55-61.
    28. Störr B, Roth J, Zeisberger E (1995).
      Thermoregulatory vasomotor reactions during endotoxin fever in guinea pigs.
      Journal of Thermal Biology 20: 431-436.
    29. Zeisberger E, Roth J (1996).
      Central regulation of adaptive responses to heat and cold.
      In: Blatteis CM, Fregly MJ (editors), Handbook of Physiology, Section 4: Environmental Physiology, Vol. 1.
      American Physiological Society, Oxford University Press: pp 579-595.
    30. Goldbach JM, Roth J, Störr B, Zeisberger E (1996).
      Repeated infusions of TNF α cause attenuation of the thermal response and influence LPS-fever in guinea pigs.
      American Journal of Physiology 270: R749-R754.
    31. Rosenthal M, Roth J, Störr B, Zeisberger E (1996).
      Fever response in lean (Fa/-) and obese (fa/fa) Zucker rats and its lack to repeated injections of LPS.
      Physiology & Behavior 59: 787-793.
    32. Goldbach JM, Roth J, Störr B, Zeisberger E (1996).
      Lack of tolerance development to tumor necrosis factor α inside the central nervous system.
      Cellular and Molecular Life Sciences (formerly: Experientia) 52: 774-777.
    33. Goldbach JM, Roth J, Zeisberger E (1997).
      Fever suppression by subdiaphragmatic vagotomy in guinea pigs depends on the route of pyrogen administration.
      American Journal of Physiology 272: R675-R681.
    34. Goldbach JM, Roth J, Störr B, Zeisberger E (1997).
      Influence of pentoxifylline on fevers induced by bacterial LPS and tumor necrosis factor α in guinea pigs.
      European Journal of Pharmacology 319: 273-278.
    35. Zeisberger E, Roth J, Störr B, Rosenthal M (1997).
      Fever and stress in lean and obese Zucker rats.
      Annals of the New York Academy of Sciences 813: 401-412.
    36. Roth J, Goldbach JM, Störr B, Zeisberger E (1997).
      Studies on the role of tumor necrosis factor α in the responses to bacterial pyrogenic stimuli.
      Annals of the New York Academy of Sciences 813: 255-263.
    37. Zeisberger E, Goldbach JM, Roth J (1997).
      Humoral and nerval transport of immune signals to the brain.
      In: Nielsen Johannsen B, Nielsen R (editors), Thermal Physiology 1997.
      ISBN 87-986468-2-6  published by the August Krogh Institute, Copenhagen, pp 293-296.
    38. Roth J, Hopkins SJ, Hoadley ME, Tripp A, Aslan T, Störr B, Luheshi G, Zeisberger E (1997).
      Fever and production of cytokines in response to repeated injections of muramyl-dipeptide in guinea pigs.
      Pflügers Archiv European Journal of Physiology 434: 525-533.
    39. Roth J, Aslan T, Störr B, Zeisberger E (1997).
      Lack of cross-tolerance between bacterial lipopolysaccharide and muramyl-dipeptide in inducing circulating TNF and IL-6.
      American Journal of Physiology 273: R1529-R1533.
    40. Goldbach JM, Roth J, Störr B, Zeisberger E (1997).
      Changes of abdominal temperature and circulating levels of cortisol and interleukin-6 in response to intra-arterial infusions of tumor necrosis factor-α or tumor necrosis factor-β in guinea pigs.
      European Journal of Pharmacology 334: 249-254.
    41. Roth J (1998).
      Immunological and neuroendocrine modulation of fever in stress.
      Progress in Brain Research 115: 177-192.
    42. Zeisberger E, Roth J (1998).
      Tolerance to pyrogens.
      In: Kluger MJ, Bartfai T, Dinarello CA (editors), Molecular Mechanisms of Fever.
      Annals of the New York Academy of Sciences 856: 116-131.
    43. Roth J, Störr B, Voigt K, Zeisberger E (1998).
      Inhibition of nitric oxide synthase results in a suppression of interleukin-1-induced fever in rats.
      Life Sciences 62: PL345-PL350.
    44. Roth J, Martin D, Störr B, Zeisberger E (1998).
      Neutralization of bacterial pyrogen-induced circulating tumour necrosis factor by its type 1 soluble receptor in guinea pigs: effects on fever and endogenous formation of interleukin-6.
      Journal of Physiology (London) 509: 267-275.
    45. Roth J, Störr B, Voigt K, Zeisberger E (1998).
      Inhibition of nitric oxide synthase attenuates LPS-induced fever without reduction of circulating cytokines in guinea pigs.
      Pflügers Archiv - European Journal of Physiology 436: 858-862.
    46. Tripp A, Roth J, Störr B, Voigt K, Zeisberger E (1998).
      Febrile tolerance develops in response to repeated administration of bacterial lipopolysaccharide but not of interleukin-1 in rats.
      Journal of Thermal Biology 23: 387-394.
    47. Lenczowski MJP, Bluthe RM, Roth J, Rees GS, Rushforth DA, Van Dam AM, Tilders FJH, Dantzer R, Rothwell NJ, Luheshi G (1999).
      Central administration of recombinant rat interleukin-6 to rats induces hypothalamus-pituitary-adrenal activation and fever, but not sickness behavior.
      American Journal of Physiology 276: R665-R672.
    48. Roth J, Störr B, Goldbach JM, Voigt K, Zeisberger E (1999).
      Dose-dependent attenuation of LPS-fever by inhibitors of inducible NO-synthase in guinea pigs.
      European Journal of Pharmacology 383: 177-188.
    49. Störr B, Roth J, Voigt K, Zeisberger E (2000).
      Local inhibition of LPS-induced hypothalamic TNF-formation by pentoxifylline has no effect on production of IL-6 within the anterior hypothalamus.
      Journal of Thermal Biology 25: 71-75.
    50. Roth J (2000).
      Hormonelle und neuroendokrine Beeinflussung der Tempreaturregulation und des Wasserhaushalts im Verlauf der thermischen Adaptation des Meerschweinchens (Cavia aperea Porcellus).
      VVB Laufersweiler Verlag - Edition Scientifique, ISBN 3-89687-549-3 , pp 1-114.
    51. Roth J, Störr B, Martin D, Voigt K, Zeisberger E (2000).
      The role of local induction of tumor necrosis factor by LPS within a subcutaneous air pouch in the development of a febrile response in guinea pigs.
      Neuroimmunomodulation 7: 169-176.
    52. Roth J (2000).
      Critical Thermal Limits.
      In: Fink G (editor-in-chief), Encyclopedia of Stress.
      Volume 1, Academic Press, San Diego, pp 598-600.
    53. Roth J (2000).
      Hyperthermia.
      In: Fink G (editor-in-chief), Encyclopedia of Stress.
      Volume 2, Academic Press, San Diego, pp. 431-438.
    54. Roth J (2000).
      Temperature Effects.
      In: Fink G (editor-in-chief), Encyclopedia of Stress.
      Volume 3, Academic Press, San Diego, pp 575-576.
    55. Töllner B, Roth J, Störr B, Martin D, Voigt K, Zeisberger E (2000).
      The role of TNF in the febrile and metabolic responses of rats to intraperitoneal injection of a high dose of LPS.
      Pflügers Archiv - European Journal of Physiology 440: 925-932.
    56. Ross G, Roth J, Störr B, Voigt K, Zeisberger E (2000).
      Afferent nerves are involved in the febrile response to injection of LPS into artificial subcutaneous chambers in guinea pigs.
      Physiology & Behavior 71: 305-313.
    57. Hübschle T, Thom E, Watson AMD, Roth J, Klaus S, Meyerhof W (2001).
      Leptin-induced nuclear translocation of STAT3 immunoreactivity in hypothalamic nuclei involved in body weight regulation.
      Journal of Neuroscience 21: 2413-2424.
    58. Roth J, De Souza GEP (2001).
      Fever induction pathways: evidence from responses to systemic or local cytokine formation.
      Brazilian Journal of Medical and Biological Research 34: 301-314.
    59. Hübschle T, Harré EM, Meyerhof W, Pehl U, Roth J, Gerstberger R (2001).
      The central pyrogenic action of interleukin-6 is related to nuclear translocation of STAT3 in the anteroventral preoptic area of the rat brain.
      Journal of Thermal Biology 26: 299-305.
    60. Ross G, Hübschle T, Bickenbach A, Zeisberger E, Gerstberger R, Roth J (2001).
      Febrile and cortisol responses induced in guinea pigs by localized peripheral inflammatory stimulation.
      Journal of Thermal Biology 26: 319-324.
    61. Roth J (2001).
      Mechanismen der Fieberentstehung und der endogenen Antipyrese: ein Experimentalmodell zur Untersuchung von Interaktionen zwischen Immunsystem und Nervensystem.
      VVB Laufersweiler Verlag - Edition Scientifique, ISBN 3-89687-560-4 , pp 1-157.
    62. Roth J, Hübschle T, Pehl U, Ross G, Gerstberger R (2002).
      Influence of systemic treatment with cyclooxygenase inhibitors on lipopolysaccharide-induced fever and circulating levels of cytokines and cortisol in guinea pigs.
      Pflügers Archiv – European Journal of Physiology 443: 411-417.
    63. Roth J (2002).
      Fieber bei Akuterkrankung: Vorteilhaft oder maladaptiv ?
      Wiener Klinische Wochenschrift 114: 82-88.
    64. Dewald M, Braun HA, Huber MT, Zwingmann D, Roth J, Voigt K (2002).
      Interactions of temperature and angiotensin II in paraventricular neurons of rats in vitro.
      Pflügers Archiv – European Journal of Physiology 444: 117-125.
    65. Harré EM, Roth J, Pehl U, Kueth M, Gerstberger R, Hübschle T (2002).
      Molecular Biology of Thermoregulation. Selected Contribution: Role of IL-6 in LPS-induced nuclear STAT3 translocation in sensory circumventricular organs during fever in rats.
      Journal of Applied Physiology 92: 2657-2666.
    66. Roth J, Persson P (2002).
      What suppresses fever in pregnancy near term ?
      American Journal of Physiology 283: R798-R799.
    67. Ross G, Hübschle T, Pehl U, Braun HA, Voigt K, Gerstberger R, Roth J (2003).
      Fever induction by localized subcutaneous inflammation in guinea pigs: the role of cytokines and prostaglandins.
      Journal of Applied Physiology 94: 1395-1402.
    68. Uno T, Roth J, Shibata M (2003).
      Influence of the hypothalamus on the midbrain tomic inhibitory mechanism on metabolic heat production in rats.
      Brain Research Bulletin 61: 129-138.
    69. Roth J (2003).
      Energie- und Wärmehaushalt, Temperaturregulation.
      In: Schmidt RF, Unsicker K (editors), Lehrbuch der Vorklinik, Teil C: Anatomie, Biochemie und Physiologie der inneren Organe.
      Deutscher Ärzte-Verlag, Köln, pp 419-436.
    70. Harré EM, Roth J, Gerstberger R, Hübschle T (2003).
      Interleukin-6 mediates lipopolysaccharide-induced nuclear STAT3 translocation in astrocytes of rat sensory circumventricular organs.
      Brain Research 980: 151-155.
    71. Yoshida K, Nakamura K, Matsumura K, Kanosue K, König M, Thiel HJ, Boldogköi Z, Toth I, Roth J, Gerstberger R, Hübschle T (2003).
      Neurons of the rat preoptic area and the raphe pallidus nucleus innervating the brown adipose tissue express prostaglandin E receptor subtype EP3.
      European Journal of Neuroscience 18: 1848-1860.
    72. Roth J, Harré EM, Rummel C, Gerstberger R, Hübschle T (2004).
      Signaling the brain in systemic inflammation: role of sensory circumventricular organs.
      Frontiers in Bioscience 9: 290-300.
    73. Roth J, Zeisberger E, Vybiral S, Jansky L (2004).
      Endogenous antipyretics: neuropeptides and glucocorticoids.
      Frontiers in Bioscience 9: 816-826.
    74. Rummel C, Hübschle T, Gerstberger R, Roth J (2004).
      Nuclear translocation of the transcription factor STAT3 in the guinea pig brain during systemic or localized inflammation.
      Journal of Physiology (London) 557.2: 671-687.
    75. Mphahlele NR, Fuller A, Roth J, Kamerman PR (2004).
      Body temperature, behavior and plasma cortisol changes induced by chronic infusion of Staphylococcus aureus in goats.
      American Journal of Physiology 287: R863-R869.
    76. Roth J, Rummel C, Harré EM, Voss T, Mütze J, Gerstberger R, Hübschle T (2004).
      Is interleukin-6 the necessary pyrogen ?
      Journal of Thermal Biology 29: 383-389.
    77. Rummel C, Barth SW, Voss T, Korte S, Gerstberger R, Hübschle T, Roth J (2005).
      Localized vs. systemic inflammation in guinea pigs: a role for prostaglandins at distinct points of the fever induction pathways ?
      American Journal of Physiology 289: R340-R347.
    78. Rummel C, Voss T, Matsumura K, Korte S, Gerstberger R, Roth J, Hübschle T (2005).
      Nuclear STAT3 translocation in guinea pig and rat brain endothelium during systemic challenge with lipopolysaccharide and interleukin-6.
      Journal of Comparative Neurology 491: 1-14.
    79. Hübschle T, Mütze J, Mühlradt PF, Korte S, Gerstberger R, Roth J (2006).
      Pyrexia, anorexia, adipsia, and depressed motors activity in rats during systemic inflammation induced by the Toll-like receptors-2 and -6 agonists MALP-2 and FSL-1.
      American Journal of Physiology 290: R180-R187.
    80. Mütze J, Roth J, Gerstberger R, Matsumura K, Hübschle T (2006).
      Immunohistochemical evidence of functional leptin receptor expression in neuronal and endothelial cells of the rat brain.
      Neuroscience Letters 394: 105-110.
    81. Steiner AA, Roth J, Romanovsky AA (2006).
      Hot, cool, and vibrant: Second international meeting on physiology and pharmacology of temperature regulation, Phoenix, Arizona, USA, March 3-6, 2006 (Editorial).
      Journal of Thermal Biology 31: 1-3.
    82. Voss T, Rummel C, Gerstberger R, Hübschle T, Roth J (2006).
      Fever and circulating cytokines induced by double stranded RNA in guinea pigs: dependence on the route of administration and effects of repeated injections.
      Acta Physiologica 187: 379-389.
    83. Miller M, Moritz A, Röcken M, Roth J, Litzke LF (2006).
      Die Akute Phase Reaktion nach minimalinvasiven Eingriffen beim Pferd (The equine acute phase response after keyhole surgery).
      Pferdeheilkunde 22: 354-360.
    84. Roth J, Rummel C, Barth S, Gerstberger R, Hübschle T (2006).
      Molecular aspects of fever and hyperthermia.
      Neurologic Clinics 24: 421-439.
    85. Roth J (2006).
      Endogenous antipyretics.
      Clinica Chimica Acta 371: 13-24.
    86. Wenzel S, Rohde C, Wingerning S, Roth J, Koida G, Schlüter KD (2007).
      Lack of endothelial nitric oxide synthase-derived nitric oxide formation favors hypertrophy in adult ventricular cardiomyocytes.
      Hypertension 49: 193-200.
    87. Vonend O, Habbel S, Stegbauer J, Roth J, Hein L, Rump LC (2007).
      a2A-adrenoceptors regulate sympathetic transmitter release in mice kidneys.
      British Journal of Pharmacology 150: 121-127.
    88. Mütze J, Roth J, Gerstberger R, Hübschle T (2007).
      Nuclear translocation of the transcription factor STAT5 in the rat brain after systemic leptin administration.
      Neuroscience Letters 417: 286-291.
    89. Voss T, Barth SW, Rummel C, Gerstberger R, Hübschle T, Roth J (2007).
      STAT3 and COX-2 activation in the guinea pig brain during fever induced by the Toll-like receptor-3 agonist polyinosinic: polycytidylic acid.
      Cell and Tissue Research 328: 549-561.
    90. Roth J (2007).
      Critical Thermal Limits.
      In: Fink G (editor-in-chief), Encyclopedia of Stress, 2nd Edition, Volume 1, Academic Press, San Diego, pp 667-669.
    91. Roth J (2007).
      Hyperthermia.
      In: Fink G (editor-in-chief), Encyclopedia of Stress, 2nd Edition, Volume 2, Academic Press, San Diego, pp 381-388.
    92. Roth J (2007).
      Temperature Effects.
      In: Fink G (editor-in-chief), Encyclopedia of Stress, 2nd Edition, Volume 3, Academic Press, San Diego, pp 717-719.
    93. Greis A, Murgott J, Rafalzik S, Gerstberger R, Hübschle T, Roth J (2007).
      Characterization of the febbrile response induced by fibroblast-stimulating lipopeptide-1 in guinea pigs.
      American Journal of Physiology 293: 293: R152-R161
    94. Hübschle T, Rafalzik S, Gerstberger R, Roth J (2007).
      Induction of fever and sickness behavior in telemetrically monitored rats during systemic inflammation induced by zymosam.
      Journal of Animal and Veterinary Advances 6: 569-577.
    95. Wuchert F, Ott D, Murgott J, Rafalzik S, Hitzel N, Roth J, Gerstberger R (2008).
      Rat area postrema microglial cells act as sensors for the Toll-like receptor-4 agonist lipopolysaccharide.
      Journal of Neuroimmunology 204: 66-74.
    96. Knorr C, Hübschle T, Murgott J, Mühlradt P, Gerstberger R, Roth J (2008).
      Macrophage-activating lipopeptide-2 (MALP-2) induces a localized inflammatory response in rats resulting in activation of brain sites implicated in fever.
      Brain Research 1205: 36-46.
    97. Wuchert F, Ott D, Rafalzik S, Roth J, Gerstberger R (2009).
      Tumor necrosis factor-a, interleukin-1b and nitric oxide induce calcium transients in distinct populations of cells cultured from the rat area postrema.
      Journal of Neuroimmunology 206: 44-51.
    98. Mayer K, Kiessling A, Ott J, Schaefer MB, Hecker M, Henneke I, Schulz R, Günther A, Wang J, Roth J, Seeger W, Kang JX (2009).
      Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids.
      American Journal of Respiratory and Critical Care Medicine 179: 474-483.
    99. Kugel D, Kochs G, Obojes K, Roth J, Kobasa D, Gray M, Haller O, Staeheli P, von Messling V (2009).
      Intranasal administration of interferon-alpha reduces seasonal influenza A virus morbidity in ferrets.
      Journal of Virology 83: 3843-3851.
    100. Soares DM, Figueiredo MJ, Martins JM, Machado RR, Kanashiro A, do Cormo Malvar D, Pessini AC, Roth J, Souza GEP (2009).
      CCL3 / MIP-1a is not involved in the LPS-induced fever and its pyrogenic activity depends on CRF.
      Brain Research 1269: 54-60.
    101. Roth J, Rummel C, Barth SW, Gerstberger R, Hübschle T (2009).
      Molecular aspects of fever and hyperthermia.
      Immunology and Allergy Clinics 29: 229-245.
    102. Greis A, Murgott J, Gerstberger R, Hübschle T, Roth J (2009).
      Effects of repeated injections of fibroblast-stimulating lipopeptide-1 on fever, formation of of cytokines, and on the responsiveness to endotoxin in guinea pigs.
      Acta Physiologica 197: 35-45.
    103. Knorr C, Marks D, Gerstberger R, Mühlradt PF, Roth J, Rummel C (2010).
      Peripheral and central cyclooxygenase (COX) products may contribute to the manifestation of brain controlled sickness responses during localized inflammation induced by macrophage-activating lipopeptide-2 (MALP-2).
      Neuroscience Letters 479: 107-11.
    104. Ott D, Murgott J, Rafalzik S, Wuchert F, Schmalenbeck B, Roth J, Gerstberger R (2010).
      Neurons and glial cells of the rat organum vasculosum laminae terminalis directly respond to lipopolysaccharide and pyrogenic cytokines.
      Brain Research 1363: 93-106
    105. Harden LM, du Plessis I, Roth J, Loram LC, Poole S, Laburn HP (2011).
      Differences in the relative involvement of peripherally released interleukin (IL)-6, brain IL-1b and prostanoids in mediating lipopolysaccharide-induced fever and sickness behavior.
      Psychoneuroendocrinology 36: 608-622
    106. Damm J, Luheshi GN, Gerstberger R, Roth J, Rummel C (2011).
      Spatiotemporal nuclear factor interleukin 6 expression in the rat brain during LPS-induced fever is linked to sustained hypothalamic inflammatory target gene induction.
      Journal of Comparative Neurology 519: 480-505
    107. Rummel C, Gerstberger R, Roth J and Hübschle T (2011). 
      Parthenolide attenuates LPS-induced fever, circulating cytokines and markers of brain inflammation in rats.
      Cytokine 56: 739-48
    108. Zeisberger E, Roth J (2011).
      Central regulation of adaptive responses to heat and cold.
      Comprehensive Physiology: 579-595
    109. Welsch J, Hübschle T, Murgott J, Kirschning C, Rummel C, Gerstberger R, and Roth J (2012).
      Fever induction by systemic stimulation with macrophage-activating lipopeptide-2 depends upon Toll-like receptor 2 but not CD36.
      Innate Immunity: 18: 541-559
    110. Damm J, Wiegand F, Harden LM, Gerstberger R, Rummel C, Roth J (2012).
      Fever, sickness behavior and expression of inflammatory genes in the hypothalamus after systemic and localized subcutaneous stimulation of rats with the Toll-like receptor 7 agonist imiquimod.
      Neuroscience 201: 166–183
    111. Horn M, Bertling A, Brodde MF, Müller A, Roth J, Van Aken H, Jurk K, Heilmann C, Peters G, Kehrel BE (2012)
      Human neutrophil alpha defensins induce formation of fibrinogen and thrombospondin-1 amyloid-like structures and activate platelets via GPIIbIIIa.
      Journal of Thrombosis and Haemostasis 10: 647-661
    112. Bertling A, Niemann S, Hussain M, Holbrook L, Stanley RG, Brodde MF, Pohl S, Schifferdecker T, Roth J, Jurk K, Müller A, Lahav J, Peters G, Heilmann C, Gibbins JM, Kehrel B (2012).
      Staphylococcal extracellular adherence protein induces platelet activation by stimulation of thiol isomerases.
      Artheriosclerosis, Thrombosis, and Vascular Biology 32: 1979-1990
    113. Ott D, Wuchert F, Murgott J, Rummel C, Gerstberger R, Roth J (2012).
      The viral mimetic polyinosinic : polycytidylic acid (poly I:C) induces cellular responses in primary cultures from rat brain sites with an incomplete blood-brain barrier.
      Neuroscience Letters 530: 64-68
    114. Harden LM, Rummel C, Luheshi GN, Poole S, Gerstberger R, Roth J (2013).
      Interleukin-10 modulates the synthesis of inflammatory mediators in the sensory circumventricular organs: implications for the regulation of fever and sickness behaviors.
      Journal of Neuroinflammation 10: 22
    115. Schmidt MJ, Roth J, Ondreka N, Kramer M, Rummel C (2013).
      A potential role for substance P and interleukin 6 in the cerebrospinal fluid of Cavalier King Charles Spaniels with neuropathic pain.
      Journal of Veterinary Internal Medicine 27: 530-535
    116. Hatzelmann T, Harden LM, Roth J, Gerstberger R (2013).
      Antipyretic effect of central [Pyr1]apelin13 on LPS-induced fever in the rat.
      Regulatory Peptides 184: 6-13
    117. Damm J, Harden L, Gerstberger R, Roth J and Rummel C (2013).
      The putative JAK-STAT inhibitor AG490 exacerbates LPS-fever, reduces sickness behavior, and alters the expression of pro- and anti-inflammatory genes in the rat brain.
      Neuropharmacology 71: 98-111
    118. Soares DM, Ott D, Melo MC, Souza GE and Roth J (2013).
      Chemokine ligand (CCL)-3 promotes an integrated febrile response when injected within pre-optic area (POA) of rats and induces calcium signaling in cells of POA microcultures but not TNF-α or IL-6 synthesis.
      Brain Behav Immun 34: 120-9
    119. Fuchs F, Damm J, Gerstberger R, Roth J, Rummel C. (2013)
      Activation of the inflammatory transcription factor nuclear factor interleukin-6 during inflammatory and psychological stress in the brain.
      J Neuroinflammation, 10: 140
    120. Harden LM, Rummel C, Laburn HP, Damm J, Wiegand F, Poole S, Gerstberger R and Roth J (2014). Critical role for peripherally-derived interleukin-10 in mediating the thermoregulatory manifestations of fever and hypothermia in severe forms of lipopolysaccharide-induced inflammation.
      Pflugers Arch, 466: 1451-1466
    121. Koenig S, Luheshi GN, Wenz T, Gerstberger R, Roth J and Rummel C (2014)
      Leptin is involved in age-dependent changes in response to systemic inflammation in the rat.
      Brain Behav Immun, 36: 128-38

    122. Bastos-Pereira AL, Fraga D, Ott D, Simm B, Murgott J, Roth J and Zampronio A (2014)
      Involvement of brain cytokines in zymosan-induced fever.
      Journal of Applied Physiology 116: 1220-1229

    123. Roth J and Blatteis CM (2014)
      Mechanisms of fever production and lysis: lessons from experimental LPS fever.
      Comprehensive Physiology 4: 1563-1604

    124. Damm J, Wiegand F, Harden LM, Wenisch S, Gerstberger R, Rummel C and Roth J (2014) Intraperitoneal and subcutaneous injections of the TLR9 agonist ODN-1668 in rats: brain inflammatory responses are related to peripheral IL-6 rather than interferons.
      Journal of Neuroimmunology, 277: 105-117
    125. Roth J (2015)
      Energiehaushalt.
      In: von Engelhardt W, Breves G (Herausgeber) Physiologie der Haustiere, 4. Auflage, Enke Verlag, Stuttgart, pp. 465-475.
    126. Roth J (2015)
      A paradoxical role for alarin in the nervous control of energy homeostasis and thermoregulation: orexigenic but hypermetabolic.
      Temperature, 2: 49-50
    127. Schneiders J, Fuchs F, Damm J, Herden C, Gerstberger R, Soares DM, Roth J and Rummel C (2015)
      The transcription factor nuclear factor interleukin 6 mediates pro- and anti-inflammatory responses during LPS-induced systemic inflammation in mice.
      Brain Behav Immun, 48: 147-164
    128. Roth J (2015)
      Who is the gatekeeper to let inflammation enter the brain? A concerted action of endothelial and perivascular cells.
      Brain, Behavior, and Immunity 48: 29-30
    129. Ott D, Simm B, Pollatzek E, Gerstberger R, Rummel C, Roth J (2015)
      Prostaglandin D2 modulates calcium signals induced by prostaglandin E2 in neurons of rat dorsal root ganglia.
      Neuroscience Letters 597: 159-163
    130. Harden LM, Kent S, Pittman QJ, Roth J (2015)
      Fever and sickness behavior: Friend or foe?
      Brain, Behavior, and Immunity 50: 322-333
    131. Roth J (2015)
      Energiehaushalt.
      In: von Engelhardt W, Breves G, Diener M, Gäbel G (Herausgeber) Physiologie der Haustiere, 5. Auflage, Enke Verlag Stuttgart, pp 482-493
    132. Simm B, Ott D, Pollatzek E, Murgott J, Gerstberger R, Rummel C, Roth J (2016)
      Effects of prostaglandin E2 on cells cultured from the rat organum vasculosum laminae terminalis and median preoptic nucleus.
      Neuroscience 313: 23-35
    133. Schmidt M J, Rummel C, Hauer J, Kolecka M, Ondreka N, McClure V, and Roth J (2016)
      Increased CSF aquaporin-4, and interleukin-6 levels in dogs with idiopathic communicating internal hydrocephalus before and decrease after ventriculo-peritoneal shunting.
      Fluids and Barriers of the CNS 13: 12
    134. Schweighöfer H, Rummel C, Roth J, Rosengarten B (2016)
      Modulatory effects of vagal stimulation on neurophysiological parameters and the cellular immune response in the rat brain during systemic inflammation.
      Intensive Care Medicine Experimental 4: 19

    135. Roth J, Horowitz M (2017)
      Inflammation, fever and body temperature under febrile conditions.
      J. Basic Clin. Physiol. Pharmacol.28: 519-520

    136. Damm J, Roth J, Gerstberger R and Rummel C (2017)
      The use of siRNA as a pharmacological tool to assess a role for the transcription factor NF-IL-6 in the brain under in vitro and in vivo conditions during LPS-induced inflammatory stimulation.
      Journal of Basic and Clinical Physiology and Pharmacology, 28: 563-571
    137. De Melo Soares D, Santos DR, Rummel C, Ott D, Melo MCC, Roth J, Calixto JB and Souza GEP (2017)
      The relevance of kalikrein-kinin system via activation of B2 receptor in LPS-induced fever in rats. Neuropharmacology, 126: 84-96
    138. Roth J (2017)
      Fever: Mediators and Mechanisms.
      In: Cavaillon JM, Singer M (Eds.), Inflammation: From Molecular and Cellular Mechanisms to the Clinic. Volume 3, Wiley-VHC, pp 861-890

    139. Prohl A, Ostermann C, Rummel C, Roth J, Reinhold P (2017)
      Circulating and brocho-alveolar interleukin-6 in relation to body temperature in an experimental model of bovine Chlamydia psittaci infection.
      PLOS ONE 12: e0189321

    140. Gommeren K, Desmas I, Garcia A, Bauer N, Moritz A, Roth J, Peeters D (2018)
      Inflammatory cytokine and C-reactive protein concentrations in dogs with systemic inflammatory response syndrome.
      Journal of Veterinary Emergency and Critical Care 28: 9-19

    141. Dangarembizi R, Erlwanger KH, Rummel C, Roth J, Madziva MT, Harden LM (2018)
      Brewer’s yeast is a potent inducer of fever, sickness behavior and inflammation within the brain.
      Brain, Behavior, and Immunity 68: 211-223

    142. Ganjam GK, Terpolilli NA, Diemert S, Eisenbach I, Hoffmann L, Reuther C, Herden C, Roth J, Plesnila N, Culmsee C (2018)
      Cylindromatosis mediates neuronal cell death in vitro and in vivo.
      Cell Death & Differentiation 25: 1394-1407

    143. Koenig S, Bredehöft J, Perniss A, Fuchs F, Roth J, Rummel C (2018)
      Age dependent hypothalamic and pituitary responses to novel environment stress or lipopolysaccharide in rats.
      Frontiers in Behavioral Neuroscience 12: 55

    144. Sickinger M, Roth J, Failing K, Wehrend A (2018)
      Serum neuropeptide concentrations in cows with intrapartum uterine torsion.
      Animal Reproduction Science 196: 193-196

    145. Leisengang S, Ott D, Gerstberger R, Rummel C, Roth J (2018)
      Effects of thermal stimulation on neurons and astrocytes cultured from the rat median preoptic nucleus.
      Neuroreport 29: 1468-1472

    146. Leisengang S, Ott D, Murgott J, Gerstberger R, Rummel C, Roth J (2018)
      Primary cultures from rat dorsal root ganglia: responses of neurons and glial cells to somatosensory or inflammatory stimulation.
      Neuroscience 394: 1-13

    147. Sickinger M, Roth J, Failing K, Wehrend A (2018)
      Serum levels of neuropeptides in cows with left abomasal displacement.
      Veterinary Sciences 5: 103

    148. Dangarembizi R, Rummel C, Roth J, Erlwanger KH, Madziva MT and Harden LM (2019)
      Pyrogenic and neuroinflammatory properties of zymosan and its potential as an alternative to live yeast in antipyretic drug testing.
      FACETS 4: 162-182
    149. Bredehöft J, Bhandari D, Pflieger JF, Schulz S, Kang JX, Laye S, Roth J, Gerstberger R, Mayer K, Spengler B and Rummel C (2019)
      Visualizing and profiling lipids in the OVLT of fat-1 and wild type mouse brains during LPS-induced systemic inflammation using AP-SMALDI MSI.
      ACS Chem. Neurosci. 10: 4394-4406

    150. Roth J (2019)
      Eating too much fat inflames the brain: This may make you hot and anxious.
      Brain Behav. Immun. 81: 14-15.

    151. Roth J (2019)
      Wärmehaushalt und Temperaturregulation.
      In: Physiologie hoch2. 1. Aufl., Hrsg. Gründer S., Schlüter K.D., pp. 479-492.
      Urban & Fischer / Elsevier GmbH, München.

    152. Gomes BRB, de Sousa GLS, Ott D, Murgott J, de Sousa MV, de Souza PEN, Roth J, Veiga-Souza FH (2019)
      Cytoglobin attenuates neuroinflammation in lipopolysaccharide-activated primary preoptic area cells via NF-kB pathway inhibition.
      Front. Mol. Neurosci. 12: 307

    153. Grabbe N, Kaspers B, Ott D, Murgott J, Gerstberger R, Roth J (2020)
      Neurons and astrocytes of the chicken hypothalamus directly respond to lipopolysaccharide and chicken interleukin-6.
      J. Comp. Physiol. B 190: 75-85

    154. Leisengang S, Ott D, Murgott J, Nürnberger F, Gerstberger R, Rummel C, Schmidt M, Roth J. (2020)

      Effects of gabapentinoids on responses of primary cultures from rat dorsal root ganglia to inflammatory or somatosensory stimulation.
      J. Basic Clin. Physiol. Pharmacol. 31: art. 20190261

    155. Abultdinova A, Jakupov I, Roth J, Failing K, Wehrend A, Sickinger M (2020)
      Association of bovine uterine involution disturbances with serum neuropeptide concentrations.
      Veterinary World 13: 1854-1857

    156. Peek V, Neumann E, Inoue T, Koenig S, Pflieger FJ, Gerstberger R, Roth J, Matsumura K, Rummel C (2020)
      Age-dependent changes of adipokine and cytokine secretion from rat adipose tissue by endogenous and exogenous Toll-like receptor agonists.
      Front. Immunol. 11: art. 1800

    157. Leisengang S, Nürnberger F, Ott D, Murgott J, Gerstberger R, Rummel C, Roth J (2020)
      Primary culture of the rat spinal dorsal horn: a tool to investigate the effects of inflammatory stimulation on the afferent somatosensory system.
      Pflügers Arch. – Eur. J. Physiol. 472: 1769-1782

    158. Guimaraes NC, Alves DS, Vilela WR, de-Souza-Ferreira E, Gomes BRB, Ott D, Murgott J, de Souza PEN, de Sousa MV, Galina A, Roth J, Fabro de Bem A, Veiga-Souza FH (2021)
      Mitochondrial pyruvate carrier as a key regulator of fever and neuroinflammation.
      Brain Behav. Immun. 92: 90-101
    159. Nürnberger F, Leisengang S, Ott D, Murgott J, Gerstberger R, Rummel C, Roth J (2021)
      Manifestation of lipopolysaccharide-induced tolerance in neuro-glial primary cultures of the rat afferent somatosensory system.
      Inflamm. Res. 70(4): 429-444 https://doi.org/10.1007/s00011-021-01440-7

    160. Roth J (2021)
      Fever.
      In: Offermanns S, Rosenthal W (eds) Encyclopedia of Molecular Pharmacology.
      Springer, Cham: pp. 659-665

    161. Peek V, Harden LM, Damm J, Aslani F, Leisengang S, Roth J, Gerstberger R, Meurer M, von Köckritz-Blickwede M, Schulz S, Spengler B and Rummel C. (2021)
      LPS Primes Brain Responsiveness to High Mobility Group Box-1 Protein.
      Pharmaceuticals 14(6): 558

    162. 162. Braun T, Sünner L, Hachenberger M, Müller C, Wietelmann A, Juenemann M, Pons-Kühnemann J, Kaps M, Gerriets T, Tschernatsch M, Roth J, Yenigün M (2021)
      Microbubble-mediated sonothrombolysis with BR38 of a venous full blood thrombus in a rat embolic stroke model
      Ann. Transl. Med. 9(13): 1061

    163. Bredehöft J, Dolga AM, Honrath B, Wache S, Mazurek S, Culmsee C, Schoemaker RG, Gerstberger R, Roth J, Rummel C (2022)
      SK channel activation alters peripheral metabolic pathways in mice but not lipopolysaccharide-induced fever and inflammation.
      J. Inflamm. Res. 15: 509-531

    164. Nürnberger F, Leisengang S, Ott D, Murgott J, Gerstberger R, Rummel C, Roth J (2022)
      Sensitization of primary cultures from rat dorsal root ganglia with lipopolysaccharide (LPS)
      requires a robust inflammatory response.
      Inflamm. Res. 71: 187-190

    165. Leisengang S, Heilen LB, Klymiuk MC, Nürnberger F, Ott D, Wolf-Hofmann K, Gerstberger R, Rummel C, Schmidt MJ, Arnhold S, Roth J (2022)
      Neuroinflammation in primary cultures of the rat spinal dorsal horn is attenuated in presence of adipose tissue derived medicinal signalling cells (AdMSCs) in a co-cultivation model.
      Mol. Neurobiol. 59: 475-494

    166. Roth J, Gäbel G (2022)
      Energiehaushalt. In: Physiologie der Haustiere. 6. Auflage,
      Eds.: Breves G, Diener M, Gäbel G, Thieme, Stuttgart, pp.504-515

    167. Simon E, Gerstberger R, Roth J (2022)
      A history of physiological research on temperature regulation in Germany. In: Blatteis CM, Taylor N, Mitchell D (Editors) Thermal Physiology – A Worldwide History.
      Springer, New York, pp. 97-200

    168. Pflieger FJ, Wolf J, Feldotto M, Nockher A, Wenderoth T, Hernandez J, Roth J, Ott D, Rummel C (2022)
      Norepinephrine inhibits lipopolysaccharide-stimulated TNF-q but not oxylipin induction in n-3 / n-6 PUFA-enriched cultures of circumventricular organs. 
      International Journal of Molecular Sciences 23: art. 8745
    169. Nürnberger F, Ott D, Claßen R, Rummel C, Roth J, Leisengang S (2022)
      Systemic lipopolysaccharide challenge induces inflammatory changes in rat dorsal root ganglia: an ex vivo study.
      International Journal of Molecular Sciences 23: art. 13124

    170. Nürnberger F, Rummel C, Ott D, Gerstberger R, Schmidt MJ, Roth J, Leisengang S (2022)
      Gabapentinoids suppress lipopolysacharide-induced interleukin-6 production in primary cell cultures of the rat spinal dorsal horn.
      Neuroimmunomodulation: accepted for publication