Unlocking Pain
Content
Pain, particularly in chronic manifestations, arises from a multifactorial etiology and presents a complex clinical and molecular phenotype. To enhance the efficacy of chronic pain management, a comprehensive understanding of the intricate interplay between clinical and molecular phenotypes, alongside underlying mechanisms, is essential. In our research unit, we employ an interdisciplinary biopsychosocial approach, integrating fields such as neurology, neuroscience, psychosomatics, psychoneuroimmunology, (clinical) psychology, veterinary medicine, molecular biology, and epigenetics. Through the utilization of state-of-the-art methodologies and in vitro models, we aim to investigate and decode the complexities of pain pathology.
Projects in process
- The chronic pelvic pain syndrome (CPPS) in men: epigenetic decoding of a complex disease regarding etiopathogenesis, comorbidities and consequential diseases
(PI: Schagdarsurengin; Cooperation partners from AZB TNNG: Krämer-Best, Peters, Kruse, Rummel, Leisengang)
- Neuro-inflammatory paths and consequences in CPPS in men: from neurological pain-phenotype to molecular mechanisms and epi-genotype
(PI: Krämer-Best and Schagdarsurengin; Cooperation partners from AZB TNNG: Peters, Kruse, Rummel, Leisengang)
- Predictors of therapy efficacy and treatment expectations in chronic pain patients
(PI: Hermann and Krämer-Best) - In vitro models to study neuroinflammatory processes in structures of the nociceptive system
(Leisengang, Cooperation partners from AZB TNNG: Rummel, Schagdarsurengin)
Active participants
FB06 Psychologie
- Prof. Dr. Christiane Hermann
FB 10 Veterinärmedizin
- Dr. Stephan Leisengang
FB 11 Medizin
- Prof. Dr. Heidrun Krämer-Best
- Prof. Dr. Eva Peters
- Prof. Dr. Undraga Schagdarsurengin
Contact person
Undraga Schagdarsurengin (undraga.schagdarsurengin@chiru.med.uni-giessen.de)
Heidrun Krämer-Best (Heidrun.Kraemer)