Publikationen
Publikationen der letzten Jahre.
| 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 |
| 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 |
Publikationen 2024
Brosinsky P, Heger J, Sydykov A, Weiss A, Klatt S, Czech L, Kraut S, Schermuly RT, Schlüter K-D, Schulz R. Does Cell-Type-Specific silencing of monoamine oxidase B interfere with the development of right ventricle (RV) hypertrophy or right ventricle failure in pulmonary hypertension? Int J Mol Sci 25, 6212; 2024; doi: 10.3390/ijms25116212
Jurida L, Werner S, Knapp F, Niemann B, Li L, Grün D, Wirth S, Weber A, Beuerlein K, Liebetrau C, Wiedenroth CB, Guth S, Kojonazarov B, Jafari L, Wiessmann N, Günther S, Braun T, Bartkuhn M, Schermuly RT, Dorfmüller P, Yin X, Mayr M, Schmitz ML, Czech L, Schlüter K-D, Schulz R, Rohrbach S, Kracht M. A common gene signature of the right ventricle in failing rat and human hearts. Nature CVR 3, 819-840, 2024; doi: 10.1038/s44161-024-004584-1
Schreckenberg R, Schulz R, Itani N, Ferdiandy P, Bencsik P, Szabados T, Rohrbach S, Niemann B, Schlüter K.-D. Inhibition of MMP2 activity mitigates N-omega-nitro-L-arginine-methyl ester (L-NAME)-induced right heart failure. Redox Biology. in press
Schlüter K-D. The use of animals in physiological science: The past, the presence, and the future. Pflüger’s Archiv - European Journal of Physiology, in press
Publikationen 2023
Knittel J, Itani N, Schreckenberg R, Heger J, Rohrbach S, Schulz R, Schlüter K-D. Monoamine oxidase A contributes to serotonin- but not norepinephrine-dependent damage of rat ventricular myocytes. Biomolecules 13; 2023
Richter K, Asci N, Singh VK, Yakoob SH, Meixner M, Zakrzewicz A, Liese J, Hecker A, Wilker S, Stumpf S, Schlüter K-D, Rohde M, Gödecke A, Padberg W, Manzini I, Schmalzing G, Grau V. Activation of endothelial NO synthase and P2X7 receptor modification mediates the cholinergic control of ATP-induced interleukin-1β release by mononuclear phagocytes. Front Immunol 14: 1140592; 2023
Weber M, Schreckenberg R, Schlüter K.-D. Uric acid deteriorates load free cell shortening of cultured adult rat ventricular cardiomyocytes via stimulation of arginine turnover. Biology 12, 4, 2023
Publikationen 2022
Atmanspacher F, Schreckenberg R, Wolf A, Grgic I, Schlüter K-D. Effect of metabolic adaptation by voluntary running wheel activity and aldosterone inhibition on renal function in female hypertensive rats. Cells 2022, 11, 3954; doi: 10.3390/cells11243954
Schreckenberg R, Dörr O, Pankuweit S, Schieffer B, Troidl C, Nef H, Hamm CW, Rohrbach S, Li L, Schlüter K-D. Effect of anti-hypertensive medication on plasma concentrations of lysyl oxidase: Evidence for aldosterone-IL-6-dependent regulation of lysyl oxidase blood concentration. Biomedicines 2022; 10:1748; doi: 10.3390/biomedicines10071748
Mattern A, Classen R, Wolf A, Pouokam E, Schlüter K-D, Wickleder MS, Diener M. Multivalent stimulation of β1 but not β2-receptors by adrenaline functionalised gold nanoparticles. Nanoscale Advances, 2022, 4: 3182-3193
Schreckenberg R, Wolf A, Szabados T, Gömöri K, Szabo IA, Agoston G, Brenner G, Bencsik P, Ferdinandy P, Schulz R, Schlüter K-D. Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) deletion but not inhibition of extracellular PCSK9 reduces infarct sizes ex vivo but not in vivo. Int. J. Mol. Sci. 2022, 23, 6512
Richter K, Papke RL, Stokes C, Roy D, Espinosa ES, Wolf PM, Hecker A, Liese J, Singh VK, Padberg W, Schlüter K-D, Rohde M, McIntosh JM, Morley BJ, Horenstein NA, Grau V, Simard AR. Comparison of the anti-inflammatory properties of two nicotinic acetylcholine receptor ligands, phosphocholine and pCF3-diEPP. Frontiers Cell Neuroscience, 2022, 16:779081
Boening A, Welk E, Heep M, Hemmerich C, Niemann B, Schlüter K-D, Taghiyev ZT. Oral application of levosimendan before ischemia/reperfusion with and without cardioplegic arrest in rats. European Journal of Cardio-Thoracic Surgery; 2022, doi: 10.1093/ejcts/ezac168
Karadedeli MS, Schreckenberg R, Kutsche HS, Schlüter K-D. Effects of voluntary exercise on the expression of browning markers in visceral and subcutaneous fat tirssue of normotensive and spontaneoulsy hypertensive rats. Pflügers Archiv – European Journal of Physiology; 2022, 474: 205-215, doi: 10.1007/s00424-021-02629-9
Publikationen 2021
Dörner A, Lynetsky O, Euler G, Landmesser U, Schlüter K-D, Heger J. Mitochondria isolated from hearts subjected to ischemia/reperfusion benefit from adenine nucleotide translocase 1 overexpression. Membranes, 2021, 11: 836; doi: 10.3390/membranes11110836
Brosinsky P, Bornbaum J, Warga B, Schulz L, Schlüter K-D, Ghigo A, Hirsch E, Schulz R, Euler G, Heger J. PI3K as mediator of apotosis and contractile dysfunction in TGFβ1-stimulated cardiomyocytes. Biology, 2021; 10:670; doi:10.3390/biology10070670
Schreckenberg R, Wolf A, Troidl C, Simsekyilmaz S, Schlüter K-D. Pro-Inflammatory vascular stress in spontaneously hypertensive rats (SHR/NHsd) associated with high physical activity cannot be attenuated by aldosterone blockade. Front. Physiol. 2021; 8: 699283, doi: 10.3389/fcvm.2021.699283; 2021
Wolf A, Kutsche HA, Atmanspacher F, Karadedeli MS, Schreckenberg R, Schlüter K-D. Untypical metabolic adaptation in spontaneously hypertensive rats to free running wheel activity includes uncoupling protein-3 (UCP-3) and proprotein convertase subtilisin/kexin type 9 (PCSK9) expression. Front Physiol 12:598723, 2021
Hirschhäuser C, Lissoni A, Görge PM, Lampe PD, Heger J, Schlüter K-D, Leybaert L, Schulz R, Boengler K. Connexin 43 phosphorylation by casein kinase 1 is essential for the cardioprotection by ischemic preconditioning. Basic Res Cardiol 116:21, 2021
Heger J, Hirschhäuser C, Bornbaum J, Sydykov A, Dempfle A, Schneider A, Braun T, Schlüter K-D, Schulz R. Cardiomyocyte-specific deletion of MAO B reduces irreversible myocardial ischemia/reperfusion injury. Free Radical Biol Med 165; 14-23, 2021
Euler G, Locquet F, Kociszewska J, Osygus Y, Heger J, Schreckenberg R, Schlüter K-D, Kenyeres E, Szabados T, Bencsik P, Ferdinandy P, Schulz R. Matrix Metalloproteinases repress hypertrophic growth in cardiac myocytes. Cardiovascular Drugs and Therapy, 2021; doi: 10.1007/s10557-020-07138-y
Publikationen 2020
Hirschhäuser C, Sydykov A, Wolf A, Esfandiary A, Bornbaum J, Kutsche HS, Boengler K, Sommer N, Schreckenberg R, Schlüter K-D, Weissmann N, Schermuly R, Schulz R. Lack of contribution of p66shc to pressure overload-induced right heart hypertrophy. Int. J. Mol. Sci. 21. 9339 (2020); doi: 10.3390/jims21249339
Wolf A, Kutsche HS, Schreckenberg R, Weber M, Li L, Rohrbach S, Schulz R, Schlüter K-D. Autocrine effects of PCSK9 on cardiomyocytes. Basic Res. Cardiol. 115: 65 (2020)
Richter K, Ogiemwonyi-Schaefer, R, Wilker S, Chaveiro AI, Agné A, Hecker M, Reichert M, Amati A-L, Schlüter K-D, Manzini I, Schmalzing G, McIntosh JM, Padberg W, Grau V, Hecker A. Amyloid beta peptide (Aβ1-42) antagonizes nicotinic inhibition of ATP-mediated monocytic interleukine-1β release. J. Clin. Medicine (2020)
Petersen A, Kutsche HS, Nippert F, Schreckenberg R, Schulz R, Schlüter K-D. Induction of proteasome subunit low molecular weight protein (Lmp)-2 is required to induce active remodeling in adult rat ventricular cardiomyocytes. Med. Sci. (2020) 8, 21; doi: 10.3390/medsci8020021
Giricz Z, Makkos A, Schreckenberg R, Pöling J, Lörchner H, Kiss K, Bencsik P, Braun T, Schulz R, Ferdinandy P, Schlüter K-D. Swiprosin-1/EFhD-2 expression in cardiac remodeling and post-infarct repair: Effect of ischemic conditioning. Int J Mol Sci (2020) 21, 3359; doi: 10.3390/ijms21093359
Steven S, Frenis K, Kalinovic S, Kvandova M, Oelze M, Helmstädter J, Hahad O, Filippou K, Kus K, Trevisan C, Schlüter K-D, Boengler K, Chlopicki S, Frauenknecht K, Schulz R, Sorensen M, Daiber A, Kröller-Schön S, Münzel T (2020) Exacerbation of adverse cardiovascular effects of aircraft noise in an animal model of arterial hypertension. Redox Biology (2020); doi: 10.1016/j.redox.2020.101515
Schreckenberg R, Klein J, Kutsche HS, Schulz R, Gömöri K, Bencsik P, Bencsik B, Agg B, Saghy E, Ferdinandy P, Schlüter K-D. Ischemic post-conditioning in rats: Responder and Non-Responder differ in transcriptome of mitochondrial proteins. J. Cell Mol Med (2020), doi: 10.1111/jcmm.15209
Kutsche HS, Schreckenberg R, Weber M, Hirschhäuser C, Rohrbach S, Li L, Niemann B, Schulz R, Schlüter K.-D. Alterations in glucose metabolism during the transition to heart failure: The contribution of UCP-2. Cells (2020) 9:552; doi: 10.3390/cells9030552
Szibor M, Schreckenberg R, Gizatullina Z, Dufour E, Wiesnet M, Dhandapani PK, Debska-Vielhaber G, Heidler J, Wittig I, Nyman TA, Gärtner U, Hall AR, Pell V, Viscomi C, Krieg T, Murphy MP, Braun T, Gellerich FN, Schlüter K-D, Jacobs HT. Respiration chain signalling is essential for adaptive remodelling following cardiac ischemia. J Cell Mol Med 2020; 00:1-15; doi: 10.1111/jcmm.15043
Publikationen 2019
Esfandiary A, Kutsche HS, Schreckenberg R, Weber M, Pak O, Kojonazarov B, Sydykov A, Hirschhäuser C, Wolf A, Haag D, Hecker M, Fink L, Seeger W, Ghofrano HA, Schermuly RT, Weißmann N, Schulz R, Rohrbach S, Li L, Sommer N, Schlüter K-D. Protection against pressure overload-induced right heart failure by uncoupling protein 2 silencing. Cardiovasc Res 2019; doi: 10.1093/cvr/cvz049
Publikationen 2018
Braun K, Atmanspacher F, Schreckenberg R, Grgic I, Schlüter K-D. Effect of free running wheel exercise on renal expression of parathyroid hormone receptor type 1 in spontaneously hypertensive rats. Physiol Rep 2018; 6: e13482; doi: 10.14814/phy2.13842
Schlüter K.-D. Tierversuche: Übertragbarkeit auf den Menschen und ihre Durchführbarkeit. Z Herz- Thorax- Gefäßchir. Doi: 10.1007/s00398-018-0268-0
Richter K., Sagawe S, Hecker A., Küllmar M, Askevold I, Damm J, Heldmann S, Pöhlmann M, Ruhrmann S, Sander M, Schlüter K-D, Wilker S, König IR, Kummer W, Padberg W, Hone AJ, McIntosh JM, Zakrzewicz AT, Koch C, Grau V. C-Reactive Protein stimulates nicotinic acetylcholine receptors to control ATP-mediated monocytic inflammaasome activation. Front Immunol 208; 9:1604; doi: 10.3389/jimmu.2018.01604
Binas D, Daniel H, Richter A, Ruppert V, Schlüter K-D, Schieffer B, Pankuweit S. The prognostic value of sST12 and galectin-3 considering different aetiologies in non-ischemic heart failure. Open Heart 2018; doi 10.1136/openhrt-2017-000750
Heidorn M, Frodermann, Böning A, Schreckenberg R, Schlüter K-D. Citrulline improves early post-ischemic recovery of rat hearts in vitro by shifting arginine metabolism from polyamines to nitric oxide formation. Clin Med Insights 2018; 12:1-5; doi 10.1177/1179546818771908
Publikationen 2017
Böning A, Attmann T, Heep N, Niemann B, Grieshaber P, Schreckenberg R, Schlüter K-D. Cardiac surgery with crystalloid cardioplegia: Improved functional recovery due to molecular adaptations in adult rat hearts. Res Cardiovasc Med; 2017: in press
Schreckenberg R, Bencsik P, Weber M, Abdallah Y, Csonka C, Gömöri K, Kiss K, Paloszi J, Pipis J, Sarközy M, Ferdinandy P, Schulz R, Schlüter K-D. Adverse effects of β-adrenergic coupling: Ischemic postconditioning failed to preserve long-term cardiac function. J Am Heart Assoc. 2017;6:e006809. Doi: 10.1161/JAHA.117.006809
Boengler K, Bencsik P, Paloszi J, Kiss K, Pipisz M, Pipis J, Ferdinandy P, Schlüter K-D, Schulz R. Lack of contribution of p66shc and its mitochondrial translocation to ischemia-reperfusion injury and cardioprotection by ischemic preconditioning. Frontiers in Physiology; 10.3389/fphys.2017.00733, 2017
Schlüter K-D, Wolf A, Weber M, Schreckenberg R, Schulz R. Oxidized low-density lipoprotein (oxLDL) affects load free cell shortening of cardiomyocytes in a proprotein convertase subtilisin/kexin 9 (PCSK9)-dependent way. Basic Res in Cardiology, doi 10.1007/s00395-017-0650-1, 2017
Nippert F, Schreckenberg R, Schlüter K.-D. Isolation and cultivation of adult cardiomyocytes. J. Vis. Exp. (), e56634, doi:10.3791/56634; 2017
Schreckenberg R, Horn A-M, da Costa Rebelo RM, Simsekyilmaz S, Niemann B, Ling L, Rohrbach S, Schlüter K-D. Effects of 6 months‘ exercise on cardiac function, structure, and metabolism in female hypertensive rats – the decisive role of lysyl oxidase and collagen III. Frontiers in Physiology; doi: 10.3389/fphys.2017.00556, 2017
Gadicherla AK, Wang N, Bulic M, Agullo-Pascual E, Lissoni A, De Smet M, Delmar M, Bultynck G, Krysko DV, Camara A, Schlüter K-D, Schulz R, Kwok WM, Leybaert L. Mitochondrial Cx43 hemichannels contribute to mitochondrial calcium entry and cell death in the heart. Basic Res Cardiol. 2017 May;112(3):27. doi: 10.1007/s00395-017-0618-1
Boengler K, Bulic M, Schreckenberg R, Schlüter K-D, Schulz R. The gap junction modifier ZP1609 improves cardiomyocyte survival following ischemia/reperfusion independent from mitochondrial connexin 43. Br J Pharmacol, 2017; doi: 10.1111/bph.13804
Wrobeln A, Schlüter K-D, Linders J, Zähres M, Mayer C, Kirsch M, Ferenz KB. Functionality of albumin-derived perfluorocarbon-based artifical oxygen carriers in the Langendorff heart. Artifical Cells, Nanomedicine, and Biotechnology. doi 10.1080/21691401.2017
Dyukova E, Schreckenberg R, Sidtikova G, Schlüter K-D. Influence of ischemic pre- and post-conditioning on cardiac expression of calcium-sensing receptor. Bio Nano Sci 7, 12-14, 2017
Publikationen 2016
Koncsos G, Varga ZV, Baranyai T, Boengler K, Rohrbach S, Li L, Schlüter K-D, Schreckenberg R, Radovits T, Olah A, Matyas C, Lux A, Al-Khrasani M, Komlodi T, Bukosza N, Mathe D, Deres L, Bartekova M, Rajtik T, Adameova A, Szigeti K, Hamar P, Helyes Z, Tretter L, Pacher P, Merkely B, Giricz Z, Schulz R, Ferdinandy P. Diastolic dysfunction in prediabetic male rats: Role of mitochondrial oxidative stress. Am. J Physiol Heart Circ Physiol 311:H927-H943, 2016; doi: 10.1152/ajpheart.00049.2016
Nippert F, Schreckenberg R, Hess A, Weber M, Schlüter K-D. The effects of swiprosin-1 on the formation of pseudopodia-like structures and β-adrenoceptor coupling in cultured adult rat ventricular cardiomyocytes. PLoS ONE 11:e0167655, 2016
Oruqaj L, Forst S, Schreckenberg R, Inserte J, Poncelas M, Baneras J, Garcia-Dorado D, Rohrbach S, Schlüter K-D. Effect of high fat diet on pulmonary expression of parathyroid hormone-related protein and its downstream targets. Heliyon 2: e00182, 2016
Gündüz D, Tanislav C, Schlüter K-D, Schulz R, Hamm C, Aslam M. Effect of tricagelor on endothelium calcium signaling and barrier function. Thromb Haemost 2016: doi 10.1160/TH16-04-0273
Brockhoff B, Schreckenberg R, Forst S, Heger J, Bencsik P, Kiss K, Ferdinandy P, Schulz R, Schlüter K-D.
Effect of nitric oxide deficiency on the pulmonary PTHrP system.
J Cell Mol Med, in Druck, 2016
Schlüter K.-D.
Life Expectancy and Intensive Dynamic and Static Sport in the Area of Pre Heart Failure Treatment Therapies.
Online International Interdisciplinary Research Journal (OIIRJ) 2016: 6:10-19
Publikationen 2015
Dyukova E, Schreckenberg R, Arens C, Sidtikova G, Schlüter K-D. The role of calcium-sensing receptors in endothelin-1-dependent effects on adult rat ventricular cardiomyocytes: Possible contribution to adaptive myocardial hypertrophy. J Cell Phyiol 2015: doi: 10.1002/jcp.25612
Schreckenberg R, Rebelo M, Deten A, Weber M, Rohrbach S, Pipicz M, Csonka C, Ferdinandy P, Schulz R, Schlüter K-D.
Specific mechanisms underlying right heart failure: The missing upregulation of superoxide dismutase-2 and its decisive role in antioxidant defense.
Antioxid Redox Signal; doi 10.1089/ars.2014.6139, 2015
Schreckenberg R, Weber P, Cabrera-Fuentes HA, Steinert I, Preissner KT, Bencsik P, Sarközy M, Csonka C, Ferdinandy P, Schulz R, Schlüter K-D.
Mechanism and consequences of the shift in cardiac arginine metabolism following ischaemia and reperfusion in rats.
Thromb Haemost 2015: 113:482-493; IP: 5,760
Publikationen 2014
Cabrera-Fuentes HA, Ruiz-Meana M, Simsekyilmaz S, Kostin S, Inserte J, Saffarzadeh M, Galuska SP, Vijayan V, Barba I, Barreto G, Fischer S, Lochnit G, Ilinskaya ON, Baumgart-Vogt E, Böning A, Lecour S, Hausenloy DJ, Liehn EA, Garcia-Dorado D, Schlüter K-D, Preissner KT.
RNase 1 prevents the damaging interplay between extracellular RNA and TNF-a in cardiac ischaemia/reperfusion injury.
Thromb Haemost 2014: 112:1110-1119; IP: 5,760
Soetkamp D, Ngyuen TT, Menazza S, Hirschhäuser C, Hendgen-Cotta UB, Rassaf T, Schlüter K-D, Böngler K, Murphy E, Schulz R.
S-nitrosylation of mitochondrial connexin 43 regulates mitochondrial function.
Basic Res Cardiol; doi 10.1007/s00395-014-0433-x; IP: 5,955
Maxeiner H, Mufti S, Krehbiel N, Dülfer F, Helmig S, Schneider J, Böning A, Matejec R, Weigand MA, Schlüter K-D, Wenzel S.
Interleukin-6 contributes to the paracrine effects of cardiospheres cultured from human, murine, and rat hearts.
J Cell Physiol, 2014: 229: 1681-1689; IP: 3,874
Pfeil U, Kuncova J, Brüggmann D, Paddenberg R, Rafiq A, Henrich M, Weigand MA, Schlüter K-D, Mewe M, Middendorff R, Slavikova J, Kummer W.
Intrinsic vascular dopamine – a key modulator of hypoxia-induced vasodilatation in splanchnic vessels.
J Physiol, 2014: 592: 1745-1756; IP: 4,544
Arens C, Uhle F, Wolff M, Röhrig R, Koch C, Schulte A, Weiterer S, Henrich M, Weigand MA, Schlüter K-D, Lichtstern C.
Effects of echinocandin preparations on adult rat ventricular cardiomyocytes.
Anaesthesist, doi 10.007/s00101-014-2289-8, 2014; IP: 0,743
Schreckenberg R, Dyukova E, Sitdikova G, Abdallah Y, Schlüter K-D.
Mechanism by which calcium receptor stimulation modifies electromechanical coupling in isolated ventricular cardiomyocytes.
Pflugers Arch – Eur J Physiol, doi 10.1007/s00424-014-1498-y, 2014; IP: 3,073
Shazzad T, Kasseckert S A, Iraqi W, Johnson V, Schulz R, Schlüter K-D, Dörr O, Parahuleva M, Hamm C, Ladilov Y, Abdallah Y.
Mechanisms involved in postconditioning protection of cardiomyocytes against acute reperfusion injury.
J Mol Cell Cardiol 58:209-216, 2013; IP: 5,218
Publikationen 2013
Hill C, Würfel A, Heger J, Meyering B, Schlüter K-D, Weber M, Ferdinandy P, Aronheim A, Schulz R, Euler G.
Inhibition of AP-1 signaling by JDP-2 overexpression protects cardiomyocytes against hypertrophy and apoptosis induction.
Cardiovasc Res 99: 121-128, 2013
Aslam M, Schlüter K-D, Rohrbach S, Rafiq A, Nazli S, Piper HM, Noll T, Schulz R, Gündüz D.
Hypoxia-reoxygenation-induced endothelial barrier failure: role of RhoA, Rac1 and myosin light chain kinase.
J Physiol 591:461-473, 2013
Shazzad T, Kasseckert S A, Iraqi W, Johnson V, Schulz R, Schlüter K-D, Dörr O, Parahuleva M, Hamm C, Ladilov Y, Abdallah Y.
Mechanisms involved in postconditioning protection of cardiomyocytes against acute reperfusion injury.
J Mol Cell Cardiol 58:209-216, 2013
Heger J, Schlüter K-D.
Renin and the IGFII/M6P receptor system in cardiac biology.
Science World J Vol. 2013, article ID 260298, 10 pages
Publikationen 2012
Meyer R, Schreckenberg R, Kraus D, Kretschmer F, Schulz R, Schlüter K-D.
Cardiac effects of osteostatin in mice.
J Physiol Pharmacol, 63, 17-22, 2012
Röthig A, Schreckenberg R, Weber K, Conzelmann C, da Costa Rebelo RM, Schlüter K-D.
Effects of nicotine on PTHrP and PTHrP receptor expression in rat coronary endothelial cells.
Cell Physiol Biochem 29, 485-492, 2012
Maxeiner H, Abdallah Y, Kuhlmann CRW, Schlüter K-D, Wenzel S.
Effects of cerivastatin on adrenergic pathways, hypertrophic growth and TGFbeta expression in adult ventricular cardiomyocytes.
Eur J Cell Biol 91, 367-374, 2012
Heger J, Abdallah Y, Shahzad T, Klumpe I, Piper HM, Schultheiss H-P, Schlüter K-D, Schulz R, Euler G, Dörner A.
Transgenic overexpression of the adenine nucleotide translocase 1 protects cardiomyocytes against TGFß1-induced apoptosis by stabilization of the mitochondrial permeability transition pore.
J Mol Cell Cardiol 53, 73-81, 2012
da Costa Rebelo RM, Schreckenberg R, Schlüter K-D.
Adverse cardiac remodelling in spontaneously hypertensive rats: acceleration by high aerobic exercise intensity.
J Physiol 590, 5389-5400, 2012
Publikationen 2011
Hinrichs S, Heger J, Schreckenberg R, Wenzel S, Euler G, Arens C, Bader M, Rosenkranz S, Caglayan E, Schlüter K-D.
Controlling cardiomyocytes length: the role of renin and PPAR-?
Cardiovasc Res 89, 344-352, 2011
Heger J, Warga B, Meyering B, Abdallah Y, Schlüter K-D, Piper HM, Euler G.
TGFß receptor acrivation enhances cardiac apoptosis via SMAD activation and concomitant NO release
J Cell Physiol 226, 2683-2690, 2011
Korf-Klingbiel M, Kempf T, Schlüter K-D, Willenbockel C, Brod T, Heineke J, Schmidt V, Jantzen F, Brandes RP, Sudgen PH, Drexler H, Molkentin JD, Wollert K.
Conditional transgenic expression of fibroblast growth factor 9 in the adult mouse heart reduces heart failure mortality after myocardial infarction.
Circulation 123: 504-514, 2011
Abdallah Y, Iraqi W, Said M, Kasseckert SA, Shahzad T, Erdogan A, Neuhof C, Gündüz D, Schlüter K-D, Piper HM, Reusxch HP, Ladilov Y.
Interplay between Ca2+ cycling and mitochondrial permeability transition pores promotes reperfusion-induced injury of cardiac myocytes.
J Cell Mol Med, 15, 2478-2485, 2011
Publikationen 2010
Wenzel S, Henning K, Habbig A, Forst S, Schreckenberg R, Heger J, Maxeiner H, Schlüter K-D.
TGF-ß1 improves cardiac performance via up-regulation of laminin receptor 37/67 in adult ventricular cardiomyocytes.
Basic Res Cardiol, 105, 621-629, 2010
Maxeiner H, Krehbiel N, Müller A, Woitasky N, Akintürk H, Müller M, Weigand M.A., Abdallah Y, Kasseckert S, Schreckenberg R, Schlüter K-D, Wenzel S.
New insights into paracrine mechanisms of human cardiac progenitor cells.
Eur J Heart Fail, 12, 730-737, 2012
Schlüter K-D, Schreckenberg R, da Costa Rebelo RM.
Interaction between exercise and hypertension in spontaneously hypertensive rats: a meta-analysis of experimental studies.
Hypertens Res, 33, 1155-1161, 2010
Mörlein C, Schreckenberg R, Schlüter K-D.
Basal ornithine decarboxylase activity modifies apoptotic and hypertrophic marker expression in post-ischemic hearts.
Open Heart Fail J, 3, 31-37, 2010
Schlüter K-D
Calcium as a first messenger
Open Heart Fail J, 3, 9-10, 2010
Publikationen 2009
Schreckenberg R, Maier T, Schlüter K-D.
Post-conditioning restores pre-ischemic receptor coupling.
Br J Pharamcol, 156, 901-908, 2009
Schlier A, Schreckenberg R, Abdallah Y, Krasteva G, Piper HM, Pfeil U, Kummer W, Schlüter K-D.
CGRP-α responsiveness of adult rat ventricular cardiomyocytes from normotensive and spontaneously hypertensive rats.
Eur J Cell Biol, 88, 227-241, 2009
Tastan I, Schreckenberg R, Mufti S, Abdallah Y, Piper HM, Schlüter K-D.
Parathyroid hormone improves contractile performance of adult rat ventricular cardiomyocytes at low concentrations in a non-acute way.
Cardiovasc Res, 82, 77-83, 2009
Maier T, Schreckenberg R, Schlüter K-D.
Effect of pre-ischemic ß-adrenoceptor stimulation on postischemic contractile dysfunction.
Life Science, 84, 437-443, 2009
Schreckenberg R, Wenzel S, da Costa Rebelo RM, Röthig A, Meyer R, Schlüter K-D.
Cell-specific effects of nitric oxide deficiency on PTH-rP responsiveness and PTH1 receptor expression in cardiovascular cells.
Endocrinology, 150, 3735-3741, 2009
Kasseckert SA, Schäfer C, Kluger A, Gligorievski D, Tillmann J, Schlüter K-D, Noll T, Sauer H, Piper HM, Abdallah Y.
Stimulation of cGMP signalling protects coronary endothelium against reperfusion induced intercellular gap formation.
Cardiovasc Res 83, 381-387, 2009
Wenzel S, Tastan I, Abdallah Y, Schreckenberg R, Schlüter K-D.
Aldosterone improves contractile function of adult rat ventricular cardiomyocytes in a non-acute way: potential relationship to the calcium paradox of aldosteronism.
Basic Res Cardiol, 105, 247, 2010
Conzelmann C, Krasteva G, Weber K, Kummer W, Schlüter K-D.
Parathyroid hormone-related peptide (PTHrP)-dependent regulation of bcl-2 and tissue inhibitor of metalloproteinase (TIMP)-1 in coronary endothelial cells.
Cell Physiol Biochem, 24, 493-502, 2009
Merline R, Lazaroski S, Babelova A, Tsalastra-Greul W, Pfeilschifter J, Schlüter K-D, Günther A, Iozzo RV, Schäfer RM, Schäfer L
Decorin deficiency in diabetic mice: Aggrevation of nephropathy due to overexpression of profibrotic factors, enhanced apoptosis and mononuclear cell infiltration.
J Physiol Pharmacol 60 (Suppl. 4), 5-13, 2009
Schlüter K-D, Schreckenberg R.
Ischemic injury and the PTH-rP system: friend or foe?
Basic Res Cardiol, 104, 424-426, 2009
Schlüter K-D, Maxeiner H, Wenzel S.
Mechanisms that regulate function of progenitor cells in myocardial infarction.
Minerva Cardioangiol 57: 203-217, 2009
Publikationen 2008
Mufti S, Wenzel S, Euler G, Piper HM, Schlüter K-D.
Angiotensin II-dependent loss of cardiac function: Mechanisms and pharmacological targets attenuating this effect.
J Cell Physiol, 271, 242-249, 2008
Piper HM, Kasseckert S, Schlüter K-D, Abdallah Y.
Pathophysiology of myocardial reperfusion injury.
Dtsch Med Wochenschr 133, 586-590, 2008
Anwar A, Schlüter K-D, Heger J, Piper H M, Euler G.
Enhanced SERCA2A expression improves contractile performance of ventricular cardiomyocytes of rat under adrenergic stimulation.
Pflügers Arch – Eur J Physiol, 457, 485-491, 2008
Schlüter K-D, Schreckenberg R, Wenzel S.
Stem cell mobilization versus stem cell homing: potential role for parathyroid hormone?
Cardiovasc Res 77, 612-613, 2008
Schermuly RT, Stasch J-P, Pullamsetti SS, Middendorff R, Müller D, Schlüter K-D, Dingendorf A, Hackemack S, Kolosionek E, Kaulen C, Dumitrascu R, Weissmann N,Mittendorf J, Klepetko W, Seeger W, Ghofrani HA, Grimminger F.
Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.
Eur Respir J, 32, 881-891, 2008
Piper HM, Abdallah Y, Kasseckert S, Schlüter K-D.
Sarcoplasmatic reticulum-mitochondrial interaction in the mechanism of acute reperfusion injury.
Cardiovasc Res 77, 234-236, 2008
Schlüter K-D, Wenzel S.
Angiotensin II: A hormone involved in and contributing to pro-hypertrophic cardiac networks and target of antihypertrophic cross-talk.
Pharmacol Therapeut 119, 311-325, 2008
Publikationen 2007
Wenzel S, Rohde C, Wingerning S, Roth J, Kojda G, Schlüter K-D.
Lack of endothelial nitric oxide (eNOS)-derived NO formation favors hypertrophy in adult ventricular cardiomyocytes. Hypertension, 49, 193-200, 2007
Sokolova J, Zimmermann R, Kreuder J, Michel-Behnke I, Schranz D, Piper HM, Schlüter K-D.
Impaired release of bioactive PTHrP in patients with pulmonary hypertension and endothelial dysfunction. J Vasc Res, 44: 67-74, 2007
Tastan H, Abdallah Y, Euler G, Piper HM, Schlüter K-D.
Contractile performance of adult ventricular rat cardiomyocytes is not directly jeoparadized by NO/cGMP-dependent induction of pro-apoptotic pathways. J Mol Cell Cardiol, 42: 411-421, 2007
Ross G, Heinemann MP, Schlüter K-D.
Vasodilatory effect of tuberoinfundibular peptide (TIP39): Requirement of receptor desensitization and its beneficial effect in the post-ischemic heart. Peptides, 28 : 878-886, 2007
Padmesekar M, Nandigama R, Wartenberg M, Schlüter K-D, Sauer H.
The acute phase protein ?2-macroglobulin induces rat ventricular cardiomyocytes hypertropghy via ERK1,2 and PI3-kinase/Akt pathways. Cardiovasc Res, 75: 109-117, 2007
Gergs U, Berndt T, Buskase J, Jones LR, Kirchhefer U, Müller FU, Schlüter K-D, Schmitz W, Neumann J.
On the role of junction in cardiac Ca2+ handling, contractility, and heart failure. Am J Physiol Heart Circ Physiol 293: H728-H734, 2007
Fontana M, Olschewski H, Olschewski A, Schlüter K-D.
Treprostinil potentiates the positive inotropic effect of catecholamines in adult rat ventricular cardiomyocytes. Br J Pharmacol., 151: 779-786, 2007
Helmig S, Schuckenböhmer P, Heger J, Euler G, Piper HM, Schlüter K-D.
Direct effects of the angiotensin-converting enzyme inhibitor ramiprilat on adult rat ventricular cardiomyocytes. Acta Physiol 191 : 267-274, 2007
Meurrens K, Ruf S, Ross G, Schleef R, von Holt K, Schlüter K-D.
Smoking accelerates the progression of hypertension-induced myocardial hypertrophy to heart in spontaneously hypertensive rats. Cardiovasc Res, 76, 311-322, 2007
Meyer R., Schreckenberg R, Kretschmer F, Bittig A, Conzelmann C, Grohé C, Schlüter K-D.
Parathyroid hormone-related protein (PTHrP) signal cascade modulates myocardial dysfunction in the pressure overloaded heart. Eur J Heart Fail 9:1156-1162, 2007
Publikationen 2006
Abdallah Y, Gkatzoflia A, Gligorievski D, Kasseckert S, Euler G, Schlüter K-D, Schäfer M, Piper HM, Schäfer C.
Insulin protects cardiomyocytes against reoxygenation-induced hypercontracture by a survival pathway targeting SRCa2+ storage. Cardiovasc Res 70:346-353, 2006
Wenzel S, Schäfer C, Abdallah Y, Piper HM, Schlüter K-D.
Contribution of PI3-kinase isoforms to angiotensin II- and ?-adrenoceptor-mediated signalling pathways in cardiomyocytes. Cardiovasc Res, 71:352-362, 2006
Abdallah Y, Ross G, Dolf A, Heinemann MP, Schlüter K-D.
N-terminal parathyroid hormone-related peptide hyperpolarizes endothelial cells and causes a reduction of the coronary resistance of the rat heart via endothelial hyperpolarization.
Peptides, 27:2927-2934, 2006
Wenzel S, Rohde C, Wingerning S, Roth J, Kojda G, Schlüter K-D.
Lack of endothelial nitric oxide (eNOS)-derived NO formation favors hypertrophy in adult ventricular cardiomyocytes.
Hypertension, DOI: 10.1161/01.HYP.0000250468.02084.ce
Sokolova J, Zimmermann R, Kreuder J, Michel-Behnke I, Schranz D, Piper HM, Schlüter K-D.
Impaired release of bioactive PTHrP in patients with pulmonary hypertension and endothelial dysfunction.
J Vasc Res, DOI: 10.1159/000098154
Tastan H, Abdallah Y, Euler G, Piper HM, Schlüter K-D.
Contractile performance of adult ventricular rat cardiomyocytes is not directly jeoparadized by NO/cGMP-dependent induction of pro-apoptotic pathways.
J Mol Cell Cardiol, DOI: 10.1016/j.yjmcc.2006.10.012
Ross G, Heinemann MP, Schlüter K-D.
Vasodilatory effect of tuberoinfundibular peptide (TIP39): Requirement of receptor desensitization and its beneficial effect in the post-ischemic heart.
Peptides, DOI: 10.1016/j.peptides.2006.12.010
K.-D. Schlüter, H.M. Piper, S. Wenzel
The role of adrenoceptors in mechanotransduction
In: Heart Mechanotransduction, eds: Weckström and Tavi, Landes Bioscience. P. 106-119, 2006
K.-D Schlüter, G. Ross
Intrakrine, parakrine und autokrine Funktionen des PTH/PTHrP-Systems
In: Molekularmedizinische Grundlagen von para- und autokrinen Regulationsstörungen, ed. Ganten und Ruckpaul, Springer-Verlag, 2006, 133-158
Publikationen 2005
Wenzel C, Müller C, Piper HM, Schlüter K-D.
p38 MAP-kinase in cultured adult rat ventricular cardiomyocytes: expression and involvement in the hypertrophic signalling
Eur J Heart Failure, 7:453-460, 2005
van Eickels M, Schreckenberg R, Doevendans PA, Meyer R, Grohé C, Schlüter K-D.
The influence of oestrogen-deficiency and ACE inhibition on the progression of myocardial hypertrophy in spontaneously hypertensive rats
Eur J Heart Failure, 7: 1079-1084, 2005
Abdallah Y, Gkatzoflia A, Pieper H, Zoga E, Walther S, Kasseckert S, Schäfer M, Schlüter K-D, Piper HM, Schäfer C
Mechanism of cGMP-mediated protection in a cellular model of myocardial reperfusion injury
Cardiovasc Res 66:123-131, 2005
Ross G, Schlüter K-D.
Cardiac-specific effects of parathyroid hormone-related peptide: Modification by aging and hypertension
Cardiovasc Res, 66:334-344, 2005
Ross G, Engel P, Abdallah Y, Kummer W, Schlüter K-D.
Tuberinfundibular peptide of 39 residues (TIP39): A new mediator of cardiac function via NO-production in the rat heart
Endocrinology, 146:2221-2228, 2005
Lütteke D, Ross G, Abdallah Y, Schäfer C, Piper HM, Schlüter K-D.
Parathyroid Hormone-related peptide improves contractile responsiveness of adult rat cardiomyocytes with depressed cell function irrespectively of oxidative inihibition.
Basic Res Cardiol., 100: 320-327, 2005
Wenzel S, Soltanpour G, Schlüter K-D.
No correlation between p38 MAPK pathway and the contractile dysfunction in diabetic cardiomyocytes
Pflügers Arch - Eur J Physiol 451: 328-337, 2005
Anwar A, Taimor G, Korkususz H, Schreckenberg R, Berndt T, Abdallah Y, Piper HM, Schlüter K-D.
PKD-independent signal transduction pathways increase SERCA2 expression in adult rat cardiomyocytes
J Mol Cell Cardiol, 39: 911-919, 2005
D. Garcia-Dorado, K.-D. Schlüter, E.A. Martinson, H.M. Piper
Which papers are most interesting to the readers of Cardiovascular Research? Information from download monitoring.
Cardiovasc Res 65:1-5, 2005 (editorial)
K.-D. Schlüter, D. Schreiber
Adult ventricular cardiomyocytes: Isolation and Culture
In: Methods in Molecular Biology, Vol. 290: Basic Cell Culture Protocols, 3rd edition, edited by Helgason CD and Miller CL. 305-314
K.-D. Schlüter, H.M. Piper, S. Wenzel
The role of adrenoceptors in mechanotransduction
In: Heart Mechanotransduction, eds: Weckström and Tavi, Landes Bioscience, im Druck
K.-D. Schlüter, H.M. Piper
Isolation and culture of adult ventricular cardiomyocytes
In: Practical Methods in Cardiovascular Research, ed. Stefan Dhein et al., Humana Press, 557-567
Publikationen 2004
Grohé, C., van Eickels, M., Wenzel, S., Meyer, R., Degenhardt, H., Doevendans, P.A., Heinemann, M.P., Ross, G., Schlüter, K.-D.
Sex specific differences in ventricular expression and function of parathyroid hormone-related peptide Cardiovasc.
Res. 61:307-316, 2004
Taimor, G., Schlüter K.-D., Best, P., Helmig, S., Piper H.M.
Transcription activator protein 1 (AP-1) mediates a - but not b -adrenergic hypertrophic growth responses in adult cardiomyocytes.
Am J Physiol (Heart Circ Physiol)
286:H2369-H2375, 2004
Schreckenberg, R., Taimor G, Piper HM, Schlüter K-D.
Inhibition of Ca 2+-dependent PKC isoforms unmasks ERK-dependent hypertrophic growth evoked by phenylephrine in adult ventricular cardiomyocytes
Cardiovasc Res, 63:553-560, 2004
H. Degenhardt, K.-D. Schlüter
The role of parathyroid hormone-related peptide in endothelium-dependent regulation of cardiac function
Current Topics in Peptide & Protein Research, 6:105-113, 2004
K.-D. Schlüter, K. Wollert
Synchronization and integration of multiple hypertrophic pathways
Cardiovasc Res, 63:367-372, 2004
K.-D. Schlüter, D. Schreiber
Adult ventricular cardiomyocytes: Isolation and culture
Meth Mol Biol 290:305-314, 2004
Publikationen 2003
Jansen, J., Gres, P., Umschlag, C., Heinzel, F.R., Degenhardt, H., Schlüter, K.-D., Heusch, G., Schulz, R.
PTHrP improves contractile function of stunned myocardium in rats and pigs Am J Physiol. 284:H49-H55, 2003
Schorr, K., Taimor, G., Degenhardt, H., Weber, K., Schlüter K.-D.
Parathyroid hormone-related peptide is induced by stimulation of ?1A-adrenoceptors and improves resistance against apoptosis in coronary endothelial cells
Mol Pharmacol 63:111-118, 2003
Inserte, J., Perelló, A., Agulló, L., Ruiz-Meana, M., Schlüter, K.-D., Escalona, N., Graupera, M., Bosch, J., Garcia-Dorado, D.
Left ventricolar hypertrophy in rats with biliary cirrhosis
Hepatology 38:589-598, 2003
Langer, M., Lütteke, D., Schlüter, K.-D.
Mechanism of the positive contractile effect of nitric oxide on rat ventricular cardiomyocytes with positive force-frequency relationship
Pflügers Arch Eur J Physiol 447:289-297, 2003
Ladilov Y, Efe Ö, Schäfer C, Rother B, Kasseckert S, Abdallah Y, Meuter K, Schlüter K.-D., Piper HM.
Reoxygenation-induced rigor-type contracture
J Mol Cell Cardiol 35:1481-1490, 2003
Publikationen 2002
Ruf S, Piper HM, Schlüter K-D.
Specific role for the extracellular signal-regulated kinase pathway in angiotensin II- but not in phenylephrine-induced cardiac hyprtrophy in vitro. Pflügers Arch Eur J Physiol. 443:483-490
Kanevskij M, Taimor G, Schäfer M, Piper HM, Schlüter K-D.
Neuropeptide Y modifies the hypertrophic response of adult ventricular cardiomyocytes to norepinpehrine. Cardiovasc Res 53:879-887
Schäfer M, Schäfer C, Piper HM, Schlüter K-D.
Hypertrophic responsiveness of cardiomyocytes to a- and b-adrenoceptor stimulation requires NHE-1 activation but not cellular alkalization. Eur J Heart Failure 4:249-254
Rosenkranz S, Amann K, Flesch M, Haeuseler C, Kilter H, Schlüter K-D, Böhm M.
Alterations of b-adrenergic signaling and cardiac hypertrophy in transgenic mice overexpressing TGF- b1. Am J Physiol Heart Circ Physiol 283:H1253-H1262
Degenhardt H, Jansen J, Schulz R, Sedding D, Braun-Dulläus R, Schlüter K-D.
Mechanosensitive release of parathyroid hormone-related peptide from coronary endothelial cells. Am J Physiol Heart Circ 283H1489-H1496
Heinemann MP, Degenhardt H, Schlüter K-D.
PTHrP steigert den Koronarfluß NO-unabhängig. MedReview 9:8
Publikationen 2001
Schäfer M, Pönicke K, Heinroth-Heffmann I, Brodde O-E, Piper HM, Schlüter K-D.
Beta-Adrenoceptor stimulation attenuates the hypertrophic effect of alpha-adrenoceptor stimulation on adult rat ventricular cardiomyocytes. J Am Coll Cardiol 37:300-307
Schlüter K-D, Katzer C, Piper HM.
A N-terminal PTHrP peptide fragment devoid of a PTH/PTHrP-receptor binding domain activates cardiac ETA receptors. Br J Pharmacol 132:427-432
Taimor G, Schlüter K-D, Piper HM.
Hypertrophy-associated gene induction after b-adrenergic stimulation in adult cardiomyocytes. J Mol Cell Cardiol 33:503-511
Flesch M, Ettelbrück S, Rosenkranz S, Maack C, Cremers B, Schlüter K-D, Zolk O, Böhm M.
Differential effects of carvedilol and metoprolol on isoprenaline-induced changes in b-adrenoceptor density and systolic function in rat cardiac myocytes. Cardiovasc. Res. 49: 371-380
Wenzel S, Taimor G, Piper HM, Schlüter K-D.
Redox sensitive intermediates mediate angiotensin II-induced p38-MAP kinase activation, AP-1 binding activity and TGF-b expression in adult ventricular cardiomyocytes. FASEB J 15:2291-2293
Wenzel S, Schorr K, Degenhardt H, Frischkopf K, Kojda G, Wiesner RJ, Rosenkranz S, Piper HM, Schlüter K-D.
TGF-b1 downregulates PTHrP in coronary endothelial cells. J Mol Cell Cardiol 33: 1181-1190
Pönicke K, Schlüter K-D, Heinroth-Hoffmann I, Seyfarth T, Goldberg M, Piper HM, Brodde E.
Noradrenaline-induced increase in protein synthesis is mediated by a1-adrenoceptors in adult rat cardiomyocytes. Naunyn Schmiedebergs Arch Pharmacol 364:444-453
Schlüter K-D.
Development of heart failure after aortic stenosis (Letter to the Editor). Circulation 101:e11
Clemens TL, Cormier S, Eichinger A, Endlich K, Fisher E, Friedman PA, Helwig JJ, Karaplis AC, Massfelder T, Rossert J, Schlüter K-D, Silve C, Stewart AF, Taesch N, Takane K.
PTHrP and its receptors: nuclear functions and roles in the renal and cardiovascular systems, the placental trophoblasts and the pancreatic islets. Br J Pharmacol 134:1113-1136