List of publications
Prof. Dr. Joachim Geyer
Bild: Rolf Wegst, SFB 1021
Wannowius M, Karakus E, Aktürk Z, Breuer J, Geyer J (2023).
Role of the Sodium-Dependent Organic Anion Transporter (SOAT/SLC10A6) in Physiology and Pathophysiology.
Int. J. Mol. Sci. 24:9926, https://doi.org/10.3390/ijms24129926.
Zakrzewicz D, Geyer J (2023).
Interactions of Na+/taurocholate cotransporting polypeptide with host cellular proteins upon hepatitis B and D virus infection: novel potential targets for antiviral therapy.
Biol. Chem. 404(7):673-690, https://doi.org/10.1515/hsz-2022-0345.
Zakrzewicz D, Geyer J (2022).
Multitasking Na+/Taurocholate Cotransporting Polypeptide (NTCP) as a Drug Target for HBV Infection: from Protein Engineering to Drug Discovery.
Biomedicines 10:196, https://doi.org/10.3390/biomedicines10010196.
Meyer MJ, Falk S, Römer S, Prinzinger C, Tacke S, Geyer J, Simm S, Tzvetkov MV (2022).
Cloning and Functional Characterization of Dog OCT1 and OCT2: Another Step in Exploring Species Differences in Organic Cation Transporters.
Int. J. Mol. Sci. 23:5100, https://doi.org/10.3390/ijms23095100.
Zakrzewicz D, Leidolf R, Kunz S, Müller SF, Neubauer A, Leiting S, Goldmann N, Lehmann F, Glebe D, Geyer J (2022).
Tyrosine 146 of the Human Na+/Taurocholate Cotransporting Polypeptide (NTCP) Is Essential for Its Hepatitis B Virus (HBV) Receptor Function and HBV Entry into Hepatocytes.
Viruses 14:1259, https://doi.org/10.3390/v14061259.
Karakus E, Schmid A, Leiting S, Fühler B, Schäffler A, Jakob T, Geyer J (2022).
Role of the Steroid Sulfate Uptake Transporter Soat (Slc10a6) in Adipose Tissue and 3T3-L1 Adipocytes.
Front. Mol. Biosci. 9:863912, doi: 10.3389/fmolb.2022.863912.
Palatini M, Müller SF, Kirstgen M, Leiting S, Lehmann F, Soppa L, Goldmann N, Müller C, Lowjaga KAAT, Alber J, Ciarimboli G, Ziebuhr J, Glebe D, Geyer J (2022).
IFITM3 Interacts with the HBV/HDV Receptor NTCP.
Viruses 14:727. https://doi.org/10.3390/v14040727.
Gramer I, Karakus E, Hartmann MF, Wudy SA, Bauer N, Moritz A, Aktürk Z, Geyer J (2021).
Urinary cortisol metabolites are reduced in MDR1 mutant dogs in a pilot targeted GC-MS urinary steroid hormone metabolome analysis.
J. vet. Pharmacol. Therap. doi: 10.1111/jvp.13050.
Nürnberger D, Wagner L, Müller SF, Leiting S, Leidolf R, Alber J, Hamann M, Geyer J (2021).
Detection of the ABCB11930_1931del TC mutation in two suspected ivermectin-sensitive cats and their relatives by a novel TaqMan allelic discrimination assay.
Front. Vet. Sci. 8:808392.
Enge AM, Kaltner F, Gottschalk C, Kin A, Kirstgen M, Geyer J, These A, Hammer H, Pötz O, Braeunung A, Hessel-Pras S (2021).
Organic cation transporter I and Na+/taurocholate co-transporting polypeptide are invovled in retrorsine- and senecionine-induced hepatotoxicity in HepaRG cells.
Mol. Nutr. Food Res. 2100800, doi: 10.1002/mnfr.202100800.
Melzer M, Schubert S, Müller SF, Geyer J, Hagen A, Niebert S, Burk J (2021).
Rho/ROCK inhibition promotes TGF-b3-induced tenogenic differentiation in mesenchymal stromal cells.
Stem Cell International, article ID 8284690, https://doi.org/10.1155/2021/8284690.
Wannowius M, Karakus E, Geyer J (2021).
Functional Analysis of Rare Genetic Variants in the Negative Regulator of Intracellular Calcium Signaling RCAS/SLC10A7.
Front. Mol. Biosci. 8:741946. doi: 10.3389/fmolb.2021.741946
Kirstgen M, Müller SF, Lowjaga KAAT, Goldman N, Lehmann F, Alakurtti S, Yli-Kauhaluoma J, Baringhaus KH, Krieg R, Geyer J (2021).
Identification of novel HBV/HDV entry inhibitors by pharmacophore- and QSAR-guided virtual screening.
Viruses 13:1489, https://doi.org/10.3390/v13081489.
Palatini M, Müller SF, Lowjaga KA, Noppes S, Alber J, Lehmann F, Goldmann N, Glebe D, Geyer J (2021).
Mutational analysis of the GXXXG/A motifs in the human Na+/taurocholate co-transporting polypeptide NTCP on its bile acid transport function and hepatitis B/D virus receptor function.
Front Mol Biosci 8:699443, doi: 10.3389/fmolb.2021.699443.
Nürnberger D, Müller SF, Hamann M, Geyer J (2021).
First sequencing of caprine Mdr1 (Abcb1) mRNA due to suspected neurological adverse drug reaction in a Thuringian goat following extra-label use of doramectin.
Front Vet Sci 8:682393, doi: 10.3389/fvets.2021.682393.
Floerl S, Kuehne A, Geyer J, Brockmoeller J, Tzvetkov MV, Hagos Y (2021).
Functional and Pharmacological Comparison of Human and Mouse Na+/Taurocholate Cotransporting Polypeptide (NTCP).
SLAS Discovery 1-10, doi: 10.1177/24725552211017500.
Grosser G, Müller SF, Kirstgen M, Döring B, Geyer J (2021).
Substrate Specificities and Inhibition Pattern of the Solute Carrier Family 10 Members NTCP, ASBT and SOAT.
Front Mol Biosci 8:689757, doi: 10.3389/fmolb.2021.689757.
Karakus E, Prinzinger C, Leiting S, Geyer J (2021).
Sequencing of the canine cytochrome P450 CYP2C41 gene an genotyping of its polymorphic occurrence in 36 dog breeds.
Front Vet Sci 8:663175, doi: 10.3389/fvets.2021.663175.
Kirstgen M, Lowjaga KAAT, Müller SF, Goldman N, Lehmann F, Glebe D, Baringhaus KH, Geyer J (2021).
Hepatitis D Virus Entry Inhibitors Based on Repurposing Intestinal Bile Acid Reabsorption Inhibitors.
Viruses 13(4):666, doi: 10.3390/v13040666.
Gorecki M, Müller SF, Leidolf R, Geyer J (2020).
Trospium chloride transport by mouse drug carriers oft he Slc22 and Slc47 families.
Int J Mol Sci 22(1):22, doi: 10.3390/ijms22010022.
Kirstgen M, Lowjaga KAAT, Müller SF, Goldmann N, Lehmann F, Alakurtti S, Yli-Kauhaluoma J, Glebe D, Geyer J (2020)
Selective Hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids.
Sci Rep 10:21772. doi: 10.1038/s41598-020-78618-2.
Lowjaga KAA, Kirstgen M, Müller SF, Goldmann N, Lehmann F, Glebe D, Geyer J (2020).
Long-term trans-inhibition of the hepatitis B and D virus receptor NTCP by taurolithocholic acid.
Am J Physiol Gastrointest Liver Physiol 320(1):G66-G80, doi: 10.1152/ajpgi.00263.2020.
Karakus E, Wannowius M, Müller SF, Leiting S, Leidolf R, Noppes S, Oswald S, Diener M & Geyer J (2020).
The orphan solute carrier SLC10A7 is a novel negative regulator of intracellular calcium signaling.
Sci Rep 10(1):7248. doi:10.1038/s41598-020-64006-3.
Iliev DI, Braun R, Sánchez-Guijo A, Hartmann M, Wudy S, Heckmann D, Bruchelt G, Rösner A, Grosser G, Geyer J & Binder G (2020).
Very High Dehydroepiandrosterone Sulfate (DHEAS) in Serum of an Overweight Female Adolescent without a Tumor.
Front Endocrinol 11:240. doi:10.3389/fendo.2020.00240
Blum L, Gul S, Ulshöfer T, Henke M, Krieg R, Berneburg I, Thomas D, Trautmann S, Kurz J, Geyer J, Geisslinger G, Becker K, Parnham MJ & Schiffmann S (2020).
In-vitro safety and off-target profile of the anti-parasitic arylmethylaminosteroid 1o.
Sci Rep 10(1):7534. doi:10.1038/s41598-020-64382-w.
Jensen O, Ansari S, Gebauer L, Müller SF, Lowjaga KAAT, Geyer J, Tzvetkov MV, Brockmüller J (2020).
A double-Flp-in method for stable overexpression of two genes.
Sci Rep 10:14018. doi:10.1038/s41598-020-71051-5.
Noppes S, Müller SF, Bennien J, Holtemeyer M, Palatini M, Leidolf R, Alber J, Geyer J (2019).
Homo- and heterodimerization is a common feature of the solute carrier family SLC10 members.
Biol Chem 400(10):1371-1384.
Leonhäuser D, Kranz J, Leidolf R, Arndt P, Schwantes U, Geyer J, Grosse JO (2019).
Expression of components of the urothelial cholinergic system in bladder and cultivated primary urothelial cells of the pig.
BMC Urology 19(1):62.
Andrea Rasche, Felix Lehmann, Alexander König, Nora Goldmann, Victor M. Corman, Andres Moreira-Soto, Andreas Geipel, Debby van Riel, Yulia A. Vakulenko, Anna-Lena Sander, Hauke Niekamp, Ramona Kepper, Mathias Schlegel, Chantal Akoua-Koffi, Breno F. C. D. Souza, Foday Sahr, Ayodeji Olayemi, Vanessa Schulze, Rasa Petraityte-Burneikiene, Andris Kazaks, Kira A. A. T. Lowjaga, Joachim Geyer, Thijs Kuiken, Christian Drosten, Alexander N. Lukashev, Elisabeth Fichet-Calvet, Rainer G. Ulrich, Dieter Glebe, Jan Felix Drexler (2019).
Highly diversified shrew hepatitis B viruses corroborate ancient origins and divergent infection patterns of mammalian hepadnaviruses.
PNAS Proc Natl Acad Sci U S A 116(34):17007-17012.
Gäns D, Rummel C, Schmidt M, Hamann M, Geyer J (2019).
Suspected neurological toxicity after oral application of fluralaner (Bravecto®) in a Kooikerhondje dog.
BMC Veterinary Research 15(1):283.
Gäns D, Leithäuser C, Hamann M, Geyer J (2019).
Adverse drug reactions after administration of emodepside/praziquantel (Profender®) in an MDR1-mutant Australian Shepherd dog: case report.
Front Vet Sci 6:296.
Karakus E, Zahner D, Grosser G, Leidolf R, Gundogdu C, Sánchez-Guijo A, Wudy SA, Geyer J (2018).
Estrone-3-Sulfate Stimulates the Proliferation of T47D Breast Cancer Cells Stably Transfected With the Sodium-Dependent Organic Anion Transporter SOAT (SLC10A6).
Front. Pharmacol. 9:941, doi: 10.3389/fphar.2018.00941.
Zeitz JO, Weber A, Most E, Windisch W, Bolduan C, Geyer J, Romberg FJ, Koch C, Eder K (2018).
Effects of supplementing rumen-protected niacin on fiber composition and metabolism of skeletal muscle in dairy cows during early lactation.
J Dairy Sci, in press, doi: 10.3168/jds.2018-14490.
Müller SF, König A, Döring B, Glebe D & Geyer J (2018).
Characterisation of the hepatitis B virus cross-species transmission pattern via Na+/taurocholate co-transporting polypeptides from 11 New World and Old World primate species.
PLoS One 13(6):e0199200.
Kaup D, Keller J, Most E, Geyer J, Eder K & Ringseis R (2018).
The carnitine status does not affect the contractile and metabolic phenotype of skeletal muscle in pigs.
Nutr Metab 15:2, doi: 10.1186/s12986-017-0238-7.
De Carvalho Dominguez Souza BF, König A, Rasche A, de Oliveira Carneiro I, Stephan N, Max Corman V, Luise Roppert P, Goldmann N, Kepper R, Franz Müller S, Völker C, Junior Souza de Souza A, Soares Gomes-Gouvêa M, Moreira-Soto A, Stöcker A, Nassal M, Roberto Franke C, Renato Rebello Pinho J, do Carmo Pereira Soares M, Geyer J, Lemey P, Drosten C, Martins Netto E, Glebe D & Drexler FJ (2018).
A novel hepatitis B virus species discovered in capuchin monkeys sheds new light on the evolution of primate hepadnaviruses.
Journal of Hepatology 68:1114-1122.
Bakhaus K, Bennien J, Fietz D, Sánchez-Guijo A, Hartmann M, Serafini R, Love CC, Golovko A, Wudy SA, Bergmann M & Geyer J (2018).
Sodium-dependent organic anion transporter (Slc10a6-/-) knockout mice show normal spermatogenesis and reproduction, but elevated serum levels for cholesterol sulfate.
Journal of Steroid Biochemistry and Molecular Biology 179:45-54.
Bennien J, Fischer T & Geyer J (2018).
Rare genetic variants in the sodium-dependent organic anion transporter SOAT (SLC10A6): Effects on transport function and membrane expression.
Journal of Steroid Biochemistry and Molecular Biology 179:26-35.
Bakhaus K, Fietz D, Kliesch S, Weidner W, Bergmann M & Geyer J (2018).
The polymorphism L204F affects transport and membrane expression of the sodium-dependent organic anion transporter SOAT (SLC10A6).
Journal of Steroid Biochemistry and Molecular Biology 179:36-44.
Grosser G, Bennien J, Sánchez-Guijo A, Bakhaus K, Döring B, Hartmann M, Wudy SA & Geyer J (2018).
Transport of steroid 3-sulfates and steroid 17-sulfates by the sodium-dependent organic anion transporter SOAT (SLC10A6).
Journal of Steroid Biochemistry and Molecular Biology 179:20-25.
Hartmann K, Bennien J, Wapelhorst B, Bakhaus K, Schumacher V, Kliesch S, Weidner W, Bergmann M, Geyer J & Fietz D(2016).
Current insights into the sulfatase pathway in human testis and cultured Sertoli cells.
Histochemistry and Cell Biology 146:737-748.
Gramer I, Kessler M & Geyer J (2016).
Detection of novel polymorphisms in the ckit gene of canine patients with lymphoma, melanoma, haemangiosarcoma, and osteosarcoma.
Veterinary Research Communications 40(2):89-95.
Grosser G, Baringhaus KH, Döring B, Kramer W, Petzinger E & Geyer J (2016).
Identification of novel inhibitors of the steroid sulfate carrier sodium-dependent organic anion transporter SOAT (SLC10A6) by pharmacophore modelling.
Molecular and Cellular Endocrinology 428:133-141.
Geyer J, Bakhaus K, Bernhardt R, Blaschka C, Dezhkam Y, Fietz D, Grosser G, Hartmann K, Hartmann MF, Neunzig J, Papadopoulos D, Sánchez-Guijo A, Scheiner-Bobis G, Schuler G, Shihan M, Wrenzycki C, Wudy SA & Bergmann M (2016).
The role of sulfated steroid hormones in reproductive processes.
Journal of Steroid Biochemistry and Molecular Biology 172:207-221. Review
Fietz D, Markmann M, Lang D, Konrad L, Geyer J, Kliesch S, Chakraborty T, Hossain H & Bergmann M(2015).
Transfection of Sertoli cells with androgen receptor alters gene expression without androgen stimulation.
BMC Molecular Biology 16:23, doi: 10.1186/s12867-015-0051-7.
Gramer I, Kessler M & Geyer J (2015).
Determination of MDR1 gene expression for prediction of chemotherapy tolerance and treatment outcome in dogs with lymphoma.
Veterinary and Comparative Oncology 13(4): 363-372.
Grosser G, Döring B, Ugele B, Geyer J, Kulling SE & Soukup ST (2015).
Transport of the soy isoflavone daidzein and its conjugative metabolites by the carriers SOAT, NTCP, OAT4, and OATP2B1.
Archives of Toxicology 89(12):2253-2263.
Schmidt S, Moncada M, Burger S & Geyer J (2015).
Expression, sorting and transport studies for the orphan carrier SLC10A4 in neuronal and non-neuronal cell lines and in Xenopus laevis oocytes.
BMC Neuroscience, 16:35, doi: 10.1186/s12868-015-0174-2.
Elmshäuser S, Straehle LC, Kranz J, Krebber R & Geyer J (2015).
Brain penetration of emodepside is increased in P-glycoprotein-deficient mice and leads to neurotoxicosis.
Journal of Veterinary Pharmacology and Therapeutics 38:74-79.
Kranz J, Hessel S, Aretz J, Petzinger E, Geyer J & Lampen A (2014).
The role of the efflux carriers Abcg2 and Abcc2 for the hepatobiliary elimination of benzo[a]pyrene and its metabolites in mice.
Chemico-Biological Interactions 224:36-41.
Elmshäuser S, Wilke A & Geyer J (2014).
Drug intolerance after administration of emodepside/praziquantel (Profender®) in MDR1-mutant dogs.
Kleintierpraxis 59(11):597-605.
Neunzig J, Sánchez-guijo A, Mosa A, Hartmann MF, Geyer J, Wudy SA & Bernhardt R (2014).
A steroidogenic pathway for sulfonated steroids: The metabolism of pregnenolone sulfate.
Journal of Steroid Biochemistry and Molecular Biology 144:324-333.
König A, Döring B, Mohr C, Geipel A, Geyer J & Glebe D (2014).
Kinetics of the bile acid transporter and hepatitis B virus receptor Na+/taurocholate cotransporting polypeptide (NTCP) in hepatocytes.
Journal of Hepatology 61:867-875.
Schweigmann H, Sánchez-Guijo A, Ugele B, Hartmann K, Hartmann MF, Bergmann M, Pfarrer C, Döring B, Wudy SA, Petzinger E, Geyer J & Grosser G (2014).
Transport of the placental estriol precursor 16a-hydroxy-dehydroepiandrosterone sulfate (16a-OH-DHEAS) by stably transfected OAT4-, SOAT-, and NTCP-HEK293 cells.
Journal of Steroid Biochemistry and Molecular Biology 143:259-265.
Schänzer A, Döring B, Ondrouschek M, Goos S, Garvalov BK, Geyer J, Acker T, Neubauer B & Hahn A (2014).
Stress induced up-regulation of SLC19A3 is impaired in biotin-thiamine-responsive basal ganglia disease.
Brain Pathology 24(3):270-279.
Alber J, Jiang L & Geyer J (2013).
CaRch1p does not functionally interact with the high-affinity Ca2+ influx system (HACS) of Candida albicans.
Yeast 30:449-457.
Grosser G, Fietz D, Günther S, Bakhaus K, Schweigmann H, Ugele B, Brehm R, Petzinger E, Bergmann M & Geyer J (2013).
Cloning and functional characterization of the mouse sodium-dependent organic anion transporter Soat (Slc10a6).
Journal of Steroid Biochemistry and Molecular Biology 138:90-99.
Drexler JF, Geipel A, König A, Corman VM, van Riel D, Leijten LM, Bremer CM, Rasche A, Cottontail VM, Maganga GD, Schlegel M, Müller MA, Adam A, Klose SM, Borges Carneiro AJ, Stöcker A, Franke CR, Gloza-Rausch F, Geyer J, Annan A, Adu-Sarkodie Y, Oppong S, Binger T, Vallo P, Tschapka M, Ulrich RG, Gerlich WH, Leroy E, Kuiken T, Glebe D & Drosten C (2013).
Bats carry pathogenic hepadnaviruses antigenically related to hepatitis B virus and capable of infecting human hepatocytes.
PNAS 110(40):16151-16156.
Janko C, Geyer J (2013).
Moxidectin has a lower neurotoxic potential but comparable brain penetration in P-glycoprotein-deficient CF-1 mice compared to ivermectin.
Journal of Veterinary Pharmacology and Therapeutics 36:275-284.
Fietz D, Bakhaus K, Wapelhorst B, Grosser G, Günther S, Alber J, Döring B, Kliesch S, Weidner W, Galuska CE, Hartmann MF, Wudy SA, Bergmann M & Geyer J (2013).
Membrane transporters for sulfated steroids in the human testis – Cellular localization, expression pattern and functional analysis.
PLoS ONE 8(5): e62638. doi:10.1371/journal.pone.0062638.
Kranz J, Petzinger E & Geyer J (2013).
Brain penetration of the OAB drug trospium chloride is not increased in aged mice.
World Journal of Urology 31(1):219-224.
Galuska CE, Hartmann MF, Sánchez-Guijo A, Bakhaus K, Geyer J, Schuler G, Zimmer KP & Wudy SA (2013).
Profiling intact steroid sulfates and unconjugated steroids in biological fluids by liquid chromatography-tandem mass spectrometry (LC-MS-MS).
Analyst 138:3792-3801.
Döring B, Lütteke T, Geyer J & Petzinger E (2012).
The SLC10 Carrier Family: Transport Functions and Molecular Structure. In: M.O. Bevensee (Ed.),
Co Transport Systems (pp. 105-168). Elsevier Inc. ISBN: 9780123943163. Book chapter
Geyer J & Janko C (2012).
Treatment of MDR1 mutant dogs with macrocyclic lactones.
Current Pharmaceutical Biotechnology 13:969-986. Review
Jiang L, Alber J, Wang J, Du W, Yang X, Li X, Sanglard D & Geyer J (2012).
The Candida albicans plasma membrane protein Rch1p, a member of the vertebrate SLC10 carrier family, is a novel regulator of cytosolic calcium homeostasis.
Biochemical Journal 444:497-502.
Held S, Gramer I, Hassdenteufel E, Neiger R & Geyer J (2012).
Lipid-infusion therapy of avermectin-induced neurotoxicosis in two dogs with homozygous nt230(del4) MDR1 mutation.
Kleintierpraxis 57(6):313-319.
Bijsmans ITGW, Bouwmeester RAM, Geyer J, Faber KN & van de Graaf SFJ (2012).
Homo- and heterodimeric architecture of the human liver Na+-dependent taurocholate cotransporting protein NTCP.
Biochemical Journal 441(3):1007-1015.
Fietz D, Geyer J, Kliesch S, Gromoll J & Bergmann M (2011).
Evaluation of CAG repeat length of androgen receptor expressing cells in human testes showing different pictures of spermatogenic impairment.
Histochemistry and Cell Biology, 136(6):689-697.
Burger S, Döring B, Hardt M, Beuerlein K, Gerstberger R & Geyer J (2011).
Co-expression studies of the orphan carrier protein Slc10a4 and the vesicular carriers VAChT and VMAT2 in the rat central and peripheral nervous system.
Neuroscience, 193:109-121.
Waterkotte B, Hambruch N, Döring B, Geyer J, Tinneberg HR & Pfarrer C (2011).
P-glycoprotein is functionally expressed in the polacenta-derived bovine caruncular epithelial cell line 1 (BCEC-1).
Placenta, 32:146-152.
Gramer I, Leidolf R, Döring B, Klintzsch S, Krämer EM, Yalcin E, Petzinger E & Geyer J (2011).
Breed distribution of the nt230(del4) MDR1 mutation in dogs.
The Veterinary Journal, 189: 67-71.
Wenge B, Geyer J & Bönisch H (2010).
The anticholinergic drugs oxybutynin and trospium chloride are substrates of the human organic cation transporters.
Naunyn-Schmiedeberg’s Archives of Pharmacology, 383:203-208.
Aretz JS & Geyer J (2010).
Detection of the CYP1A2 1117C>T polymorphism in 14 dog breeds.
Journal of Veterinary Pharmacology and Therapeutics, 34:98-100.
Geyer J, Gavrilova O & Schwantes U (2010).
Differences in the brain penetration of the anticholinergic drugs trospium chloride and oxybutynin.
UroToday International Journal, doi:10.3834/uiju.1944.5784.2010.02.12.
Visser WE, Wong WS, Van Mullem AAA, Friesema ECH, Geyer J & Visser TJ (2010).
Study of the transport of thyroid hormone by transporters of the SLC10 family.
Molecular and Cellular Endocrinology, 315:138-145.
Klintzsch S, Meerkamp K, Döring B & Geyer J (2009).
Detection of the nt230(del4) MDR1 mutation in dogs by a fluorogenic 5’ nuclease TaqMan allelic discrimination method.
The Veterinary Journal, 185:272-277.
Geyer J, Gavrilova O & Petzinger E (2009).
The role of P-glycoprotein in limiting brain penetration of the peripherally acting anticholinergic overactive bladder drug trospium chloride.
Drug Metabolism and Disposition, 37:1371-1374.
Cavalcanti MCO, Rizgalla M, Geyer J, Failing K, Litzke LF & Bergmann m (2009).
Expression of histone 1(H1) and testis-specific histone 1 (H1t) genes during stallion spermatogenesis.
Animal Reproduction Science, 111: 220-234.
Geyer J, Gavrilova O & Petzinger E (2008).
Brain penetration of ivermectin and selamectin in mdr1a,b P-glycoprotein and bcrp deficient knockout mice.
Journal of Veterinary Pharmacology and Therapeutics, 32: 87-96.
Geyer J, Fernandes CF, Döring B, Burger S, Godoy JR, Rafalzik S, Hübschle T, Gerstberger R & Petzinger E (2008).
Cloning and molecular characterization of the orphan carrier protein Slc10a4: Expression in cholinergic neurons of rat central nervous system.
Neuroscience, 152(4):990-1005.
Gavrilova O, Geyer J & Petzinger E (2007).
In vivo relevance for mrp2-mediated biliary excretion of the Amanita mushroom toxin demethylphalloin.
Biochimica et Biophysica Acta – Biomembranes, 1768(9):2070-2077.
Fernandes C, Godoy JR, Döring B, Cavalcanti MCO, Bergmann M, Petzinger E & Geyer J (2007).
The novel putative bile acid transporter SLC10A5 is highly expressed in liver and kidney.
Biochemical and Biophysical Research Communications 361(1):26-32.
Geyer J, Klintzsch S, Meerkamp K, Wöhlke A, Distl O, Moritz A & Petzinger E (2007).
Detection of the nt230(del4) MDR1 mutation in White Swiss Shepherd dogs: case reports of doramectin toxicosis, breed predisposition, and microsatellite analysis.
Journal of Veterinary Pharmacology and Therapeutics, 30(5):482-485.
Godoy JR, Fernandes CF, Döring B, Beuerlein K, Petzinger E & Geyer J (2007).
Molecular and phylogenetic characterization of a novel putative membrane transporter (SLC10A7), conserved in vertebrates and bacteria.
European Journal of Cell Biology, 86(8):445-460.
Geyer J, Döring B, Meerkamp K, Ugele B, Bakhiya N, Fernandes CF, Godoy JR, Glatt H & Petzinger E (2007).
Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10A6).
Journal of Biological Chemistry, 282(27):19728-19741.
Greven H, Kowalewski MR, Hoffmann B, Geyer J, Rex-Haffner M, Ugele B & Schuler G (2007).
Bovine placental steroid sulphatase: Molecular cloning and expression pattern in placentomes during gestation and at parturition.
Placenta, 28(8-9):889-897.
Linek J, Spiess B, Dallmeyer C & Geyer J (2007).
Ivermectin intoxication in three dogs with and without MDR1 gene mutation caused by vermicide paste licensed for use in horse.
Tierärztliche Praxis Ausgabe Kleintiere Heimtiere, 35(4):272-278.
Petzinger E & Geyer J (2006).
Drug transporters in pharmacokinetics.
Naunyn-Schmiedeberg’s Archives of Pharmacology 372(6):465-475. Review
Geyer J, Wilke T & Petzinger E (2006).
The Solute Carrier Family SLC10: more than a family of bile acid transporters regarding function and phylogenic relationships.
Naunyn-Schmiedeberg’s Archives of Pharmacology 372(6):413-431. Review
Geyer J, Döring B, Godoy JR, Leidolf R, Moritz A & Petzinger E (2005).
Frequency of the nt230(del4) MDR1 mutation in Collies and related dog breeds in Germany.
Journal of Veterinary Pharmacology and Therapeutics, 28(6):545-551.
Geyer J, Döring B, Godoy JR, Moritz A & Petzinger E (2005).
Development of a PCR-based diagnostic test detecting a nt230(del4) MDR1 mutation in dogs: verification in a moxidectin-sensitive Australian Shepherd.
Journal of Veterinary Pharmacology and Therapeutics, 28(1):95-99.
Geyer J, Godoy JR & Petzinger E (2004).
Identification of a sodium-dependent organic anion transporter from rat adrenal gland.
Biochemical and Biophysical Research Communications, 316(2):300-306.
Geyer J, Döring B, Failing F & Petzinger E (2004).
Molecular cloning and functional characterization of the bovine (Bos Taurus) Organic anion transporting polypeptide Oatp1a2 (Slco1a2).
Comparative Biochemistry and Physiology, Part B, 137(3):317-329.
Stracke H, Hammes HP, Werkmann D, Mavrakis K, Bitsch I, Netzel M, Geyer J, Köpcke W, Sauerland C, Bretzel RG & Federlin KF (2001).
Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats.
Experimental and Clinical Endocrinology and Diabetes 109:330-336.
Geyer J, Netzel M, Bitsch I, Frank T, Bitsch R, Krämer K & Hoppe PP (2000).
Bioavailability of water- and lipid-soluble thiamin compounds in broiler chickens.
International Journal for Vitamin and Nutrition Research 70(6):311-316.