Dr. Hanano Yamada (PhD)

External Ph.D. Student

Office: IAEA-FAO, Seibersdorf, Austria

h.yamada

Curriculum Vitae

Ph.D. Project

“The effects of handling and treatment conditions during exposure to ionizing radiation on the reproductive biology of the human disease vectors Aedes aegypti, Ae. albopictus and Anopheles arabiensis, and the development and formulation of a standardized protocol for the irradiation of these insects in the frame of the sterile insect technique”

It has been the general consensus that both X-rays and gamma-rays will induce the same or similar effects in insects when exposed to the same dose, and that the same dose of radiation will produce comparable results no matter what type of irradiator is used for the exposure. It has also been assumed that the same species will have the same or similar radio sensitivity no matter the geographic location, or the number of generations it has been kept in colonization. However, there are increasing incidences of diverging results obtained by different researchers in terms of sterility in male mosquitoes induced by irradiation and their subsequent mating propensity. Thus, there is a need to investigate these discrepancies and identify significant variable parameters within the irradiation processes with the aim to develop optimal, standardized sterilization protocols in the frame of the sterile insect technique for the management of mosquitoes. 

Publications 

(1st, 2nd or last author publications)

Yamada, H, Zhang, D, Parker, AG & Vreysen, MJ (2023) Sterilizing insects with X rays or gamma rays-which irradiator to select? 2023. Frontiers in Tropical Diseases, 4, 1224386.

Yamada H, Kaboré BA, Bimbilé Somda NS, Ntoyi NL, De Beer CJ, Bouyer J, Caceres C, Mach RL, Gómez-Simuta Y (2023) Suitability of the blood X-ray irradiator Raycell MK2 for the irradiation of three target pests of the sterile insect technique: dose response in fruit flies, tsetse flies and mosquitoes. Insects, 14(1), 92

Yamada H, Maïga H, Kraupa C, Bimbilé Somda NS, Mamai W, Wallner T, and Bouyer J (2023) Radiation dose-fractionation in adult Aedes aegypti mosquitoes. Parasite (Paris, France), 30, 5-5

Gómez-Simuta Y, Parker A, Cáceres C, Vreysen MJ & Yamada H (2021) Characterization and dose-mapping of an X-ray blood irradiator to assess application potential for the sterile insect technique (SIT). Applied Radiation and Isotopes, 176, 109859.

Somda, NS, Yamada H, Kraupa C, Mamai W, Maiga H, Kotla SS., ... & Bouyer J (2022) Response of male adult Aedes mosquitoes to gamma radiation in different nitrogen environments. Frontiers in Bioengineering and Biotechnology 10-2022 

Yamada H. and A. Parker (2022) Gafchromic™ MD-V3 and HD-V2 film response depends little on temperature at time of exposure. Journal of Radiation physics and Chemistry 196:110101

Yamada H, Maiga H, Kraupa C, Mamai W, Bimble NS et al. (2022) Effects of chilling and anoxia on the irradiation dose-response in adult Aedes mosquitoes. Front. Bioeng. Biotechnol. 10:856780.

Yamada H, Dias VS, Parker AG, Vreysen MJB, Mamai W et al. (2022) Radiation dose-rate is a neglected critical parameter in dose–response of insects. Scientific Reports 12: 6242

Yamada H, Maiga H, Bimbilé Somda NS, Carvalho DO, Mamai W, Kraupa C, Parker AG, Weltin G, Abrahim A, Wallner T, Schetelig MF, Caceres C, and Bouyer J (2020) The role of oxygen depletion and subsequent radioprotective effects during irradiation of mosquito pupae in water. Parasites Vectors 13:198  

Yamada H, Maiga H, Juarez J, De Oliveira Carvalho D, Mamai W, Ali A, Bimbile‑Somda NS, Parker AG, Zhang D, Bouyer J (2019) Identification of critical factors that significantly affect the dose‑response in mosquitoes irradiated as pupae. Parasites & Vectors 12:435

Tang Z, Yamada H, Kraupa C, Canic S, Busquets N, Talavera S, Jiolle D, Vreysen MJB, Bouyer J, Abd-Alla AMM (2020) High sensitivity of one-step real-time reverse transcription quantitative PCR to detect low virus titers in large mosquito pools. Par & Vect 13:460.

Bouyer J, Yamada H, Pereira R, Bourtzis K, & Vreysen MJ (2020) Phased conditional approach for mosquito management using sterile insect technique. Trends in Parasitology, 36(4), 325-336

Yamada H, Kraupa C, Lienhard C, Parker AG, Maiga H, Carvalho D, Zheng M, Wallner T, and Bouyer J (2019) Mosquito mass rearing: who’s eating the eggs? Parasite 26, 75.

Yamada H, Vreysen MJB, Bourtzis K, Tschirk W, Chadee D, and Gilles JRL (2015) The Anopheles arabiensis genetic sexing strain ANO IPCL1 and its application potential for the sterile insect technique in integrated vector management programmes. Acta Tropica, 142:138-144

Yamada H, Vreysen MJB, Gilles J, and Damiens D (2014) Evaluation of the competitiveness of radio-sterilised males against wild-type males of the species Anopheles arabiensis genetic sexing strain “ANO IPCL1” in semi-field cages. Malaria Journal, 13:318

Yamada H, Parker AG, Oliva CF, Balestrino F, and Gilles JRL (2014) X- Ray induced sterility in Aedes albopictus. J. Med. Entomol., 51: 811-816

NDO C, Yamada H, Damiens DD, N’DO, Gilles JRL (2013) X-ray sterilization of An. arabiensis at pupal and adult stages. Acta Tropica, 131:124-128

Yamada H, Soliban SM, Vreysen MJB, Chadee DD, and Gilles JRL (2013) Eliminating female Anopheles arabiensis by spiking blood meals with toxicants as a sex separation method in the context of the sterile insect technique. Parasites & Vectors, 6:197

Yamada H, Chhem-Kieth S, Vreysen MJB,  Rathor MN,  Gilles JRL and Cannavan A (2013) Anopheles arabiensis egg treatment with dieldrin for sex separation leaves residues in male adult mosquitoes that can bioaccumulate in goldfish (Carassius auratus auratus). Environ Toxicol Chem., 32(12):2786-91

Yamada H, Benedict MQ, Malcolm CA, Oliva CF, Soliban SM and Gilles JRL (2012) Genetic sex separation of the malaria vector, Anopheles arabiensis, by exposing eggs to dieldrin. Malar. J, 11:208

Talks & Presentations

77th Annual American Mosquito Control Association conference, Annaheim, CA. 2011. Oral presentation: “The potential of using the Sterile Insect Technique as part of the integrated management of mosquito-borne diseases”

79th Annual American Mosquito Control Association conference, Atlantic City, NJ. 2013. Oral presentation: "Feasibility of eliminating female mosquitoes by spiking blood meals for male-only releases in the context of the sterile insect technique" 

79th Annual American Mosquito Control Association conference, Atlantic City, NJ. 2013.Poster presentation: "X-Ray induced sterility in Aedes albopictus (Diptera: Culicidae) and male longevity following irradiation"

FAO/IAEA Coordinated Research Project Meeting on Exploring Genetic, Molecular, Mechanical and Behavioural Methods of Sex Separation in Mosquitoes.2013. Oral presentation: “Spiking bloodmeals for the elimination of female An. arabiensis from release material”. 

82th Annual American Mosquito Control Association conference, Savannah, GA. 2016. Oral presentation: "Efficient mosquito rearing for autocidal approaches to control invasive container breeding mosquitoes"

TC Interregional & Regional Latin America Meeting, “Sterile insect technique-based approaches to control mosquito vectors that transmit Zika, and other diseases”

25th International Congress of Entomology, Orlando, FL. 2016. Oral presentation: “Sterile insect technique-based approaches to control mosquito vectors that transmit Zika, Dengue, and other diseases” 

84th Annual American Mosquito Control Association conference, Orlando, FL. 2019. Oral presentation: “New developments in the use of the sterile insect technique (SIT) against mosquitoes”