Chetan Munegowda
PhD student
Department of General Zoology and Developmental Biology
Justus-Liebig-University, Giessen
Heinrich-Buff-Ring 38 CVH
D-35392 Giessen
Phone: +49 (0) 641 99-35788
E-mail
Fields of interest
- Genome sequencing and assembly
- Comparative and functional genomics
- Trait evolution and development in arthropods
Research
My collaborators and I aim to understand the mechanisms behind the evolutionary adaptations in arthropods, including spiders and insects. We specifically focus on how these organisms acquire novel traits, such as wings and silk production. By analyzing their genetic makeup, we explore gene duplication and its effects on trait development. Our approach combines comparative genomic analyses and advanced methodologies to uncover the regulatory mechanisms that determine the retention or loss of duplicated genes and their impact on phenotypic traits. Through this research, we aim to enhance the broader understanding of evolutionary dynamics in arthropods and their diverse adaptations.
Scientific Career
- since 2022: PhD student at the Department of General Zoology and Developmental Biology at Justus Liebig University Giessen (JLU), Germany
- 2022: Master of Science in Computational Modeling and Simulation with specialization in Computational Life Sciences at Dresden University of Technology (TUD), Germany
- 2019: Bachelor of Technology in Chemical Engineering at National Institute of Technology Karnataka (NITK), India
Selected Publications
Research Gate | Google Scholar | ORCiD
- Bukhman YV, Morin PA, Meyer S, Chu LF, Jacobsen JK, Antosiewicz-Bourget J, Mamott D, Gonzales M, Argus C, Bolin J, Berres ME, Fedrigo O, Steill J, Swanson SA, Jiang P, Rhie A, Formenti G, Phillippy AM, Harris RS, Wood JMD, Howe K, Kirilenko BM, Munegowda C, Hiller M, Jain A, Kihara D, Johnston JS, Ionkov A, Raja K, Toh H, Lang A, Wolf M, Jarvis ED, Thomson JA, Chaisson MJP, Stewart R. 2024. A High-Quality Blue Whale Genome, Segmental Duplications, and Historical Demography. Molecular Biology and Evolution 41, msae036. https://doi.org/10.1093/molbev/msae036.
- Kirilenko BM, Munegowda C, Osipova E, Jebb D, Sharma V, Blumer M, Morales AE, Ahmed AW, Kontopoulos DG, Hilgers L, Lindblad-Toh K, Karlsson EK; Zoonomia Consortium‡; Hiller M. 2023. Integrating gene annotation with orthology inference at scale. Science 380, eabn3107. https://doi.org/10.1126/science.abn3107.
- Toh H, Yang C, Formenti G, Raja K, Yan L, Tracey A, Chow W, Howe K, Bergeron LA, Zhang G, Haase B, Mountcastle J, Fedrigo O, Fogg J, Kirilenko B, Munegowda C, Hiller M, Jain A, Kihara D, Rhie A, Phillippy AM, Swanson SA, Jiang P, Clegg DO, Jarvis ED, Thomson JA, Stewart R, Chaisson MJP, Bukhman YV. A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes. BMC Biology 20, 245. https://doi.org/10.1186/s12915-022-01427-8.
Selected Conference Contributions:
- Munegowda, C., 2023. The role of large-scale gene duplications in phenotypic diversity of spiders. 5th Global Invertebrate Genomics Alliance Conference, Cartagena, CO. Oral presentation and poster.
- Munegowda, C., 2023. The role of large-scale gene duplications in phenotypic diversity of spiders. 115th DZG Annual Meeting, University of Kassel, DE. Oral presentation and poster.
- Munegowda, C., 2023. Gene and genome duplication and phenotypic novelties – Insights from spiders and insects. Spider Genomics, Development, and Evolution Workshop, Durham University, UK. Oral presentation.
- Munegowda, C., Kumar, R., Gupta, D., 2019. Structure Based Drug Design of PTP-SHP2 Inhibitors Using Virtual Screening of NCI Library. 8th International Engineering Symposium, Graduate School of Science & Technology, Kumamoto University, JP. Oral presentation.
External Links
Latest update: June 13, 2024