Neurovascular Interface
Content
Neurovascular diseases represent a great socioeconomic burden, with an increasing prevalence to be further expected due to demographic changes. In this context, the different compartments of the brain as well as the adjoining organs including the eye form a functional network with mutual interactions both on the cellular and subcellular level. Addressing underlying mechanisms of this neurovascular network, which will help understand and form new therapeutic strategies, represents the major scope of the neurovascular interface section of the TNNG. Participants of the Neurovascular Interface section study the aforementioned organ spanning network using both preclinical and clinical scientific approaches. Focusing on cerebrovascular diseases like stroke and others, state-of-the-art neuroscience techniques ranging from in vitro towards in vivo research including clinical studies are applied to foster a deeper understanding of interorgan communication processes in the context of neurovascular diseases.
Projects in process
- Acute and chronic hypoxic mitochondrial signaling for regulation of cerebral blood flow and the blood-brain-barrier
- The neuronal-endothelial-glia cell interface under ischemic conditions – implications for post-stroke regeneration
Active participants
FB08 Biologie und Chemie
- Prof. Dr. Ivan Manzini
FB10 Veterinärmedizin
- Prof. Dr. Rummel
FB11 Medizin
- Prof. Dr. Till Acker
- Dr. Hermann Cuntz
- Prof. Dr. Thorsten Döppner
- Prof. Dr. Dr. Hagen Huttner
- Prof. Dr. Peter Jedlička
- PD Dr. Attila Nemeth
- Prof. Dr. Dr. Knut Stieger
Contact person
Hagen Huttner (Hagen.Huttner@med.jlug.de )