Winter School 2015
Program of the 2015 IRTG Winter School
5th Winter School of the Collaborative Research Centre TRR81
“Chromatin Changes in Differentiation and Malignancies” Marburg-Giessen-Bad Nauheim-Rotterdam
at the Kleinwalsertal, February 22-27, 2015
Sunday 22.2.2015
20:15 Ski Rental
Monday 23.2.2015
MORNING SESSION
09:00-11:30
Chair: Angelina Georgieva and Marti Quevedo
Welcome at the seminar room - Sjaak Philipsen
- Tobias Zimmermann (PI Bartkuhn G) Efficient NGS data analyzes with Conveyer workflow engine
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Ruben Boers (PI Gribnau R) Retrospective analysis of gene expression
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Hannah Berberich (PI Bauer M) Molecular Characterization of the Interaction between PRMT4, Mi-2 and c-Myb in Hematopoietic Cells
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Maria Mikropoulou (PI Philipsen R) Reactivation of the fetal γ-globin gene in adult erythropoiesis: screening for candidate γ-globin repressive proteins
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Ikram Ullah (PI Brehm M) dMi-2 and RNA
12:00-17:00 Open Discussions
17:30-18:15 Dinner
EVENING SESSION
18:30-21:30
Chair: Ina Theofel and Ruben Boers
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Gaby Rijsdijk (PI Gribnau R) X chromosome deletions in all shapes and sizes
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Ilona Vuist (PI Houtsmuller R) Transcription coupled repair and chromatin structure
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Fan Wu (PI Braun/Zhou BN) DNA modification in developing and adult heart
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Rob Swenker (PI Nellist R) Generation of TSC2 knock-out cell lines by CRISPR/CAS9-mediated genome engineering
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Tim Hundertmark (PI Rathke M) Chromatin changes in post-meiotic germ cell stages of Drosophila
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Adna Omeragic (PI Gribnau R) The function of lncRNAs in chromosome silencing: comparison between mammals and marsupials
Tuesday 24.2.2015
08:00-09:00 Breakfast
MORNING SESSION
09:00-11:30
Chair: Andrea Enguita and Karim Bouazoune
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Igor Mačinković (PI Brehm M) Characterization of CoREST complexes in Drosophila
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Titia G Meijer (PI Umar R) Elucidation of the role of Programmed cell death 4 in Estrogen Receptor positive breast cancer cell lines treated with 4-hydroxy-tamoxifen
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Sara Völkel (PI Suske M) Zinc finger independent genome-wide binding of Sp2 potentiates recruitment of histone-fold protein Nf-y distinguishing it from Sp1 and Sp3
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Silvia Hoeboer (PI Philipsen R) Reactivation of fetal hemoglobin expression: functional analysis of candidate modifiers in vivo
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Angelina Georgieva (PI Braun/Zhou BN) Linking high order chromatin reorganization to stem cell homeostasis by H3K56ac and Sirt6
12:00-17:00 Open Discussions
17:30-18:15 Dinner
EVENING SESSION
18:30-21:30
Chair: Maria Mikropoulou and Jean Schneikert
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Estrellia Uijl (PI Hoorn R) The role of Toll-like receptor 9 and cell-free mitochondrial DNA in a mouse model of hypertension
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Ina Theofel (PI Rathke M) The tBRD trio - regulators of a testis-specific transcription program
- Andreas Enguita-Marruedo (PI Baarends R) Live imaging of histone removal in differentiating mouse spermatids
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Peeyush Sahu (PI Bauer M) Analysis of the genome-wide PRMT6 binding profile
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Johan Slotman (PI Houtsmuller R) Revealing mechanisms in double stranded break
repair during meiosis using nanoscopy
PI meeting in the seminar room
Wednesday 25.2.2015
Morning SESSION
9:00-11:30
Chair: Ilona Vuist and Benedetto Giaimo
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Yanhan Jia (PI Dobreva BN) The role of Lamin B1 in lung cancer
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Ruben Dries (PI Huylebroeck R) Transcriptional dynamics in a TGFbeta centric
relational network during early neurogenesis -
Markus Seibert (PI Schmitz G) Identification and characterization of new histone phosphorylation sites
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Azadeh Amirnasr (PI Wiemer R) Clinical relevance of deregulated microRNAs in NF1-associated Malignant peripheral nerve sheath tumors
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Francesca Ferrante (PI Borggrefe G) Site-specific methylation ofNotch1 by CARM1 controls amplitude and duration of the Notch1 response
12:00-17:00 Open Discussions
17:30-18:15 Dinner
EVENING SESSION
18:30-21:30
Chair: Azadeh Amirnasr and Markus Seibert
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Johan Brandsma (PI Poot R) Classifying transcription regulators in embryonic stem cells
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Kristina Kovac (PI Brehm M) Cancer relevant mutations in CHD4/Mi-2 mutants
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Niels Galjart (PI R) A fluOmic view of CTCF
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Jean Schneikert (PI Stiewe M) Exploring the sequence requirements of cis-regulatory genomic regions by multiplex CRISPR-ChIP
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Joost Gribnau (PI R) The sense of nonsense
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Benedetto Daniele Giaimo (PI Borggrefe G) A phospho-dependent mechanism controls a committed chromatin state at Notch target genes
Thursday 26.2.2015
08:00-09:00 Breakfast
MORNING SESSION
09:00-11:30
Chair: Hannah Berberich and Ruben Dries
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Marti Quevedo (PI Poot R) Mediator and Super-Enhancers in Neural Stem Cells
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Martin Schneider (PI Borggrefe G) Mediator of Transcriptional Regulation in Notch Signaling
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Mike Broeders (PI Pijnappel R) Development of a stem cell-based therapy for
mucopolysaccharidosis type VI -
Amandine Charras (PI Braun/Zhou BN) Chromatin organization and nuclear size control
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Kerstin Wendt (PI R) Cohesin-related developmental syndromes
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Sjaak Philipsen Closing remarks
12:00-16:00 Open Discussions
16:00-17:30 Workshops on Perspectives
17:30-18:30 Farewell Dinner and events:
19:00-20:00 Torch-light procession
20:00-late Farewell party
Friday 27.2.2015
Download the program in PDF format here!