Winter School 2016
Program of the 2016 IRTG Winter School
6th Winter School of the Collaborative Research Centre TRR81
“Chromatin Changes in Differentiation and Malignancies” Marburg-Giessen-Bad Nauheim-Rotterdam
at the Kleinwalsertal, February 21-26, 2016
Sunday 21.2.2016
20:00 Ski Rental
Monday 22.2.2016
MORNING SESSION
09:00-11:30
Chair: Silvia Hoeboer and Francesca Ferrante
Welcome at the seminar room - Sjaak Philipsen
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Ruben Boers (PI Gribnau R) MeD-seq, a novel method to detect genome wide DNA methylation
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Joachim Boers (PI Gribnau R) MeD-seq, a novel method to detect genome wide DNA methylation
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Guangshuai Jia (PI Braun BN) Single cell transcriptomics reveals heterogeneity of the cardiac progenitor cells
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Jente van Staalduinen (PI Grosveld R) Pioneer transcription factors as key regulators of haematopoiesis
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Jonathan Lenz (PI Brehm M) Establishing CRISPR/Cas9 for genomic tagging of proteins in a Drosophila melanogaster cell line
- Izampela Zampeta (PI Huylebroeck R) A pair of Soxs for Zeb2: cross - talk among pluripotency network related transcription factors during epiblast pluripotency exit and neural commitment
12:00-17:00 Open Discussions
17:30-18:15 Dinner
EVENING SESSION
18:30-21:30
Chair: Johan Slotman and Kristina Kovac
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Hegias Mira Bontenbal (PI Gribnau R) Generation of an X Chromosome Reactivation mouse model
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Peeyush Sahu (PI Bauer M) Genome-wide binding of PRMT6 and histone modification signature in NT2/D1 cells
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Chantal Voskamp (PI Gribnau R) Single-cell analysis of heterozygous Rnf12 mice to study the regulation of X chromosome inactivation
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Xiang Li (PI Braun BN) Epigenetic regulation of cardiomyocyte proliferation and heart regeneration
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Martijn Bogaerts (PI Philipsen R) Finding a network profile for hemoglobin switching
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Parysatis Sachs (PI Mermoud M) Genome-wide analysis of the ATP-dependent remodeler SMARCAD1 and its impact on TFIIIC function
Tuesday 23.2.2016
08:00-09:00 Breakfast
MORNING SESSION
09:00-11:30
Chair: Sreya Basu and Rui Gao
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Malgorzata Sotomska (PI Borggrefe G) Characterization of the polycomb group protein L3MBTL2 in Notch signaling
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Laura Brückner (PI van Steensel A) Context-dependent effects of HP1 assessed in high throughput by thousands of integrated reporters
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Yanhan Jia (PI Dobreva BN) The role of Lamin B1 in lung cancer migration and metastasis
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Stefano Rivetti (PI Wendt R) Epilepsy in Cornelia de Lange Syndrome
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Andrea Nist (PI Stiewe M) Widespread epigenetic activation of ∆Np73 in small cell lung cancer causes vulnerability to Tip60-p400 inhibition
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Martí Quevedo (PI Poot R) Discovery of new factors MEDIATing transcription
12:00-17:00 Open Discussions
17:30-18:15 Dinner
EVENING SESSION
18:30-21:30
Chair: Joachim Boers and Igor Mačinković
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Francesca Ferrante (PI Borggrefe G) HDAC3 as a positive modulator of Notch signaling
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Aristea Magaraki (PI Baarends R) Round spermatid injection rescues female lethality of a paternally inherited Xist deletion in mouse
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Tim Hundertmark (PI Rathke M) Chromatin interactors in post-meiotic germ cell development of Drosophila
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Johan Slotman (PIs Houtsmuller R, Baarends R) Revealing mechanisms in double stranded break repair during meiosis using nanoscopy
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Rui Gao (PI Dobreva BN) The role of Rnf20 in heart development
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Jana Haas (PI Schmitz G) Analysis of HIPK2-dependent gene regulation
Wednesday 24.2.2016
Morning SESSION
9:00-11:30
Chair: Hegias Mira Bontenbal and Ina Theofel
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Eva Brinkman (PI van Steensel A) Quantitative analysis of NHEJ fidelity and kinetics
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Markus Seibert (PI Schmitz G) Characterization of mitotic histone phosphorylation
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Isabel Gordaliza Alaguero (PI Poot R) Uncovering autism protein interaction networks in neural stem cells
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Aleksandra Turkiewicz (PI Borggrefe G) Characterization of the transcription factor RBP-J in mature T-lymphocytes
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Teresa Robert Finestra (PI Gribnau R) Gene dosage imbalance in cancer
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Kristina Kovac (PI Brehm M) Cancer relevant mutations in CHD4/Mi-2 mutants
12:00-17:00 Open Discussions
17:30-18:15 Dinner
EVENING SESSION
18:30-21:30
Chair: Aristea Magaraki and Tim Hundertmark
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Esther Sleddens-Linkels (PI Baarends R) Pericentric heterochromatin in murine Primordial Germ Cells (PGCs)
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Ina Theofel (PI Rathke M) The epigenetic readers tBRD-1 and tBRD-2 cooperate to guarantee transcription of a defined set of genes in spermatocytes
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Silvia Hoeboer (PI Philipsen R) Reactivation of fetal hemoglobin expression: functional analysis of candidate modifiers in vivo
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Dong Ding (PI Mermoud M) ATP-Dependent Chromatin Remodeling in Pluripotency: the SMARCAD1 interactome
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Nuo Yu, (PI Galjart R) Induced Pluripotent Stem-Cell Models for Cardiac Disease
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Ilona Vuist (PIs Houtsmuller R, Verschure A) UV-induced transcription stalling and transcript decay
Thursday 25.2.2016
08:00-09:00 Breakfast
MORNING SESSION
09:00-11:30
Chair: Ilona Vuist and Xiang Li
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Meneka Rupasinghe (PI Verrijzer R) Determination of instrumental subunits of the ATP-dependent NuRD chromatin remodelling complex during myogenic differentiation
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Carolin Witte (PI Bauer M) Characterization of PRMT6 knock-out MEFs
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Guillaume Giraud (PI Grosveld R) FLI-1 and the LDB1 complex: A group of friends playing together during erythroleukemia
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Bastian Stielow (PI Suske M) Targeting mechanisms of the non-canonical Polycomb repressive complex PRC1.6
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Sreya Basu (PI Galjart R) A novel role for dynamic MTs in ES cell maintenance
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Igor Mačinković (PI Brehm M) CoREST complexes in Drosophila
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Sjaak Philipsen Closing remarks
12:00-16:00 Open Discussions
16:00-17:30 Workshops on Perspectives
17:30-18:30 Farewell Dinner and events:
19:00-20:00 Torch-light procession
20:00-late Farewell party
Friday 26.2.2016
Download the program in PDF format here!